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DAPK3 and RPL34
Data Source:
BioGRID
(two hybrid)
DAPK3
RPL34
Description
death associated protein kinase 3
ribosomal protein L34
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Actin Filament
PML Body
Membrane Raft
Endoplasmic Reticulum
Cytosol
Cytosolic Large Ribosomal Subunit
Extracellular Exosome
Molecular Function
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Protein C-terminus Binding
CAMP Response Element Binding Protein Binding
Small GTPase Binding
Identical Protein Binding
Protein Homodimerization Activity
Leucine Zipper Domain Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
Cadherin Binding
Biological Process
Chromatin Organization
Regulation Of Transcription, DNA-templated
Protein Phosphorylation
Apoptotic Process
Regulation Of Smooth Muscle Contraction
Regulation Of Mitotic Nuclear Division
Regulation Of Mitotic Cell Cycle
Regulation Of Cell Shape
Regulation Of Autophagy
Negative Regulation Of Translation
Neuron Differentiation
Positive Regulation Of Cell Migration
Intracellular Signal Transduction
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Regulation Of Myosin II Filament Organization
Protein Autophosphorylation
Regulation Of Focal Adhesion Assembly
Cellular Response To Interferon-gamma
Positive Regulation Of Canonical Wnt Signaling Pathway
Apoptotic Signaling Pathway
Regulation Of Cell Motility
Regulation Of Actin Cytoskeleton Reorganization
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Translation
Translational Initiation
SRP-dependent Cotranslational Protein Targeting To Membrane
Viral Transcription
Pathways
Caspase activation via Dependence Receptors in the absence of ligand
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one
4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid
(4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile
Fostamatinib
Diseases
GWAS
Age-related macular degeneration (
23326517
)
Expressive vocabulary in infants (
25226531
)
Apolipoprotein A1 levels (
32203549
)
Blond vs. brown/black hair color (
30531825
)
Height (
25282103
)
Interacting Genes
15 interacting genes:
AATF
AK3
ATF4
CDKN1A
CHEK2
DAXX
GRB14
MDM2
MET
NEDD4L
PAWR
PRKCZ
RPL34
TCP10L
TP53
7 interacting genes:
APP
CDK4
CDK5
DAPK3
MAX
PTEN
SRPK2
Entrez ID
1613
6164
HPRD ID
04478
17996
Ensembl ID
ENSG00000167657
ENSG00000109475
Uniprot IDs
B3KNJ3
O43293
A1LUY1
P49207
PDB IDs
1YRP
2J90
3BHY
3BQR
5A6N
5A6O
5VJA
4UG0
4V6X
5AJ0
5LKS
5T2C
6EK0
6IP5
6IP6
6IP8
6LQM
6LSR
6LSS
6LU8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6W6L
6XA1
6Y0G
6Y2L
6Y57
6Y6X
6Z6L
6Z6M
6Z6N
6ZM7
6ZME
6ZMI
6ZMO
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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