DEUP1 and ING5

Data Source:
BioGRID (two hybrid)

		DEUP1	ING5
Description		deuterosome assembly protein 1	inhibitor of growth family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Deuterosome	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Identical Protein Binding	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Centriole Replication Cell Projection Organization De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Multi-ciliated Epithelial Cell Differentiation	DNA Replication Protein Acetylation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Apoptotic Signaling Pathway
Pathways			HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS			Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494)
Interacting Genes		44 interacting genes: AMPH ARL16 BRMS1L CCDC187 CCDC85B CCHCR1 CEP57 DGCR6 DGCR6L DTNB ESRRG EXOC5 FAM50B FBF1 GEM GOLGA2 HAUS8 HGS IFIT3 ING5 KCTD9 KIFC3 KRT15 KRT28 KRT3 LNX1 NTAQ1 PIAS2 PPP1R13B RUNX1T1 SKIL SUMO1 TBC1D22B TFPT TRIM54 TXLNA TXLNB USHBP1 ZFHX3 ZNF148 ZNF460 ZNF572 ZNF655 ZNF835	47 interacting genes: APC APLP1 ARFIP2 BARD1 BEX3 BRPF1 C3orf62 CBY2 CCDC33 CCHCR1 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH GGA1 GRIPAP1 HAP1 HGS HTT ICA1 IKZF3 JADE2 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 ODF2 PCM1 PRMT5 RCOR3 SMARCE1 SUOX TADA3 TAF1D THAP6 TP53 TRIML2 VIM WASF1
Entrez ID		159989	84289
HPRD ID		08689	16348
Ensembl ID		ENSG00000165325	ENSG00000168395
Uniprot IDs		E9PLX9 Q05D60	A0A1B0GW41 Q8WYH8
PDB IDs			3C6W 5ME8 5MTO
Enriched GO Terms of Interacting Partners?
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