IQUB and ALX4

Data Source:
BioGRID (two hybrid)

		IQUB	ALX4
Description		IQ motif and ubiquitin domain containing	ALX homeobox 4
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GO Annotations	Cellular Component	Acrosomal Vesicle Motile Cilium	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding HMG Box Domain Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Smoothened Signaling Pathway Cilium Assembly	Skeletal System Development Hair Follicle Development Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Post-embryonic Development Anterior/posterior Pattern Specification Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Embryonic Digit Morphogenesis Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Digestive Tract Development Embryonic Skeletal System Morphogenesis Roof Of Mouth Development
Pathways
Drugs
Diseases			Frontonasal dysplasia Enlarged parietal foramina/cranium bifidum
GWAS			Blood pressure measurement (high sodium intervention) ( 24165912) Brain morphology (MOSTest) ( 32665545) Cadmium levels ( 26025379) Excessive hairiness ( 29895819) Gout ( 22179738) Male-pattern baldness ( 29146897 27182965) Monobrow ( 27182965) Response to antidepressants in depression ( 29998114) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)
Interacting Genes		57 interacting genes: ALX4 ANAPC11 ANKRD23 BHLHB9 BLZF1 CALCOCO2 CEP70 CEP76 CYSRT1 DIP2A DYNLL1 EYA2 FAM107A GOLGA2 IHO1 KATNAL1 KIFC3 KRT40 KRT75 KRT76 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 KRTAP12-4 LHX3 MAGEA6 MDFI PATZ1 PIH1D2 PIK3R3 PKP3 POU6F2 PRDM6 PRR23D1 PRR23D2 RHOH SAXO1 SMN1 SMN2 SORBS3 SYCE1 TMCC2 TP53BP2 TRAF2 TRAF6 TRIM23 TRIM27 TRIM42 TRIM50 TRIM54 TRIM55 TRIM63 ZNF143 ZNF410 ZNF526 ZRANB1	14 interacting genes: ALX1 CEBPE EMX1 FOXA3 GATA4 HOXA3 HOXB13 HOXB6 HOXD3 IQUB LEF1 PARVG SOX10 SOX2
Entrez ID		154865	60529
HPRD ID		08194	05661
Ensembl ID		ENSG00000164675	ENSG00000052850
Uniprot IDs		A0A024R771 Q8NA54	Q9H161
PDB IDs		2DAF	2M0C
Enriched GO Terms of Interacting Partners?
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