ZCWPW2 and PBX2

Data Source:
BioGRID (two hybrid)

		ZCWPW2	PBX2
Description		zinc finger CW-type and PWWP domain containing 2	PBX homeobox 2
Image			No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	Protein Binding Zinc Ion Binding Methylated Histone Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Transcription Factor Binding
	Biological Process		Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Animal Organ Morphogenesis Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Neuron Development
Pathways
Drugs
Diseases
GWAS		Cognitive decline (age-related) ( 28078323) Gut microbiota relative abundance (Eubacterium belonging to family Erysipelotrichaceae) ( 33208821) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494)	Advanced age-related macular degeneration ( 26691988) Asthma ( 21804548 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947) Coronary artery disease ( 33020668) Crohn's disease ( 23266558) Inflammatory bowel disease ( 28067908) Moderate to vigorous physical activity levels ( 29899525) Prostate cancer ( 23535732) Refractive error ( 32231278) Rheumatic heart disease ( 32488134) Ulcerative colitis ( 28067908)
Interacting Genes		3 interacting genes: HSF2BP PBX2 UBC	37 interacting genes: BAIAP2 BFSP2 BLOC1S1 BLOC1S5 BRMS1L CARD9 CCDC88B CDCA7L CENPBD1 COPS6 DCTN3 EFHC1 ELP1 FAM90A1 HOXA1 HOXA5 HOXA9 HOXB5 HOXB8 HOXC5 HOXC8 HOXC9 MCRS1 MSC MTREX NUP62 PBX1 PKNOX1 PPFIBP1 RIPPLY2 RPL4 RPS6KC1 SMYD3 UBE2E1 ZCWPW2 ZDHHC7 ZNF587
Entrez ID		152098	5089
HPRD ID		19107	08890
Ensembl ID		ENSG00000206559	ENSG00000204304
Uniprot IDs		Q504Y3	A0A024RCR3 P40425
PDB IDs		4O62 4Z0O 4Z0R
Enriched GO Terms of Interacting Partners?
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