CNIH3 and VSIR

Data Source:
BioGRID (two hybrid)

		CNIH3	VSIR
Description		cornichon family AMPA receptor auxiliary protein 3	V-set immunoregulatory receptor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane ER To Golgi Transport Vesicle Membrane Dendrite AMPA Glutamate Receptor Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Dendritic Shaft Synapse Postsynaptic Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Channel Regulator Activity	Protein Binding Enzyme Binding Identical Protein Binding Endopeptidase Activator Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Synaptic Transmission, Glutamatergic Regulation Of Membrane Potential COPII Vesicle Coating Regulation Of AMPA Receptor Activity	Positive Regulation Of Gene Expression Positive Regulation Of Endopeptidase Activity Positive Regulation Of Cell Migration Zymogen Activation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Regulatory T Cell Differentiation Regulation Of Immune Response Positive Regulation Of Collagen Catabolic Process Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Negative Regulation Of CD8-positive, Alpha-beta T Cell Proliferation
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER
Drugs
Diseases
GWAS		Cancer ( 29299148) Gut microbiota relative abundance (Streptococcus) ( 33208821) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Opioid dependence ( 26239289) White blood cell count ( 32888494)
Interacting Genes		28 interacting genes: AQP6 BIK CD79A CEACAM3 CLDN20 ERGIC3 FAM210B FNDC9 GPX8 KCNN4 LEUTX LMNA LRRC25 NEMP1 ODF4 PLD3 SLC16A2 SMIM3 SORT1 STOM SUSD3 TMEM14B TMEM237 TMEM31 TMEM52B TMEM80 TMPRSS2 VSIR	27 interacting genes: APOD ASGR1 ATP6V0C BMP10 C14orf180 CCL4L2 CLEC7A CLRN2 CNIH3 DOLK MS4A13 PLPP6 PLPPR2 PLSCR1 SLC35B1 SLC35B4 SMAD3 SMCO4 TMEM100 TMEM14C TMEM218 TMEM229B TMEM97 TNF TSPAN2 TSPO2 VAMP3
Entrez ID		149111	64115
HPRD ID		08799	15160
Ensembl ID		ENSG00000143786	ENSG00000107738
Uniprot IDs		Q8TBE1	Q9H7M9
PDB IDs			6MVL 6OIL 6U6V
Enriched GO Terms of Interacting Partners?
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