KASH5 and ITM2B

Data Source:
BioGRID (two hybrid)

		KASH5	ITM2B
Description		KASH domain containing 5	integral membrane protein 2B
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Lateral Element Nuclear Outer Membrane Integral Component Of Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Meiotic Spindle Pole	Golgi Membrane Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Endosome Membrane Membrane Golgi-associated Vesicle Membrane Integral Component Of Organelle Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding Dynein Complex Binding	Amyloid-beta Binding Protein Binding ATP Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Actin Filament Organization Homologous Chromosome Pairing At Meiosis Spermatogenesis Telomere Localization Oogenesis Spindle Assembly Spindle Localization Microtubule Cytoskeleton Organization Involved In Homologous Chromosome Segregation Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation	Nervous System Development Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Cellular Protein Metabolic Process
Pathways			Amyloid fiber formation
Drugs
Diseases
GWAS
Interacting Genes		112 interacting genes: ABHD1 ADIPOQ ANKRD46 ATF7 BAG5 BCL2L2 BET1 C14orf180 CCDC120 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CMTM5 CRABP2 CTXN3 CWF19L2 CXCL16 CXCL9 CYBC1 DERL1 DNAJC30 EFNA5 EMD FAM161A FAM241B FAM50B FAM90A1 FATE1 FIS1 FRA10AC1 FTCD FXYD3 GABARAPL2 GALNT2 GIMAP5 GOSR2 GPATCH4 GPR25 HMOX1 ITGAM ITM2B JAGN1 KDM1A LARP1 LAT LENG1 LHFPL5 LMNA LRCH4 MALL MARCHF2 MFSD5 MMP14 MOSPD3 MS4A1 MTX2 NRIP3 NSG1 NTAQ1 OLFM4 PDGFRA PGAP2 PGRMC1 PIGU PLP2 PLPP6 PPP1R18 RIPPLY2 RNF146 RSPH14 RSRC2 RTP2 SENP2 SERP2 SGTA SHMT2 SLC30A2 SLC35B4 SLC41A1 SLC41A2 SLC5A4 SLN SMCO4 SNAP47 STBD1 STX12 STX5 TCF25 TMEM11 TMEM147 TMEM14C TMEM19 TMEM199 TMEM41A TMEM86A TMPRSS4 TNF TRAF3IP3 TRARG1 TSHZ3 TTC23 UPK1B UPK2 VAMP1 VAMP2 VAMP4 VTI1B ZC2HC1C ZFPL1 ZNF250	7 interacting genes: APP BCL2 CREB3 KASH5 LMNA NAALADL2 SYNE4
Entrez ID		147872	9445
HPRD ID		08134	04878
Ensembl ID		ENSG00000161609	ENSG00000136156
Uniprot IDs		Q8N6L0	A0A384MDP7 Q9Y287
PDB IDs		6R2I
Enriched GO Terms of Interacting Partners?
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