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CSTF1 and MIRLET7I
Data Source:
BioGRID
(unspecified method)
CSTF1
MIRLET7I
Description
cleavage stimulation factor subunit 1
microRNA let-7i
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
MRNA Cleavage Stimulating Factor Complex
Extracellular Space
Nucleus
Cytoplasm
Extracellular Vesicle
Molecular Function
RNA Binding
Protein Binding
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
Sequence-specific Single Stranded DNA Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
MRNA Splicing, Via Spliceosome
Termination Of RNA Polymerase II Transcription
MRNA 3'-end Processing
Negative Regulation Of Gene Expression
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Defense Response To Protozoan
Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Cognitive decline (age-related) (
28078323
)
Interacting Genes
12 interacting genes:
BARD1
BRCA1
CSTF3
H2AC20
MIR140
MIR206
MIR92A2
MIRLET7A3
MIRLET7I
POLR2A
TOLLIP
VCP
113 interacting genes:
AGO2
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CDC5L
CELF1
CELF2
CHERP
CPSF1
CRTAP
CSTF1
CSTF3
DARS1
DDX1
DDX21
DDX23
DDX3X
DHX36
DHX37
EIF2AK2
ELAVL1
EPRS1
ERAL1
ESRP1
FAM98A
FIP1L1
FUS
G3BP2
GRSF1
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
P3H1
PAXBP1
PDCD11
PLOD1
PLRG1
PTBP1
PUF60
PUM1
PURA
PURB
QARS1
RARS1
RBFOX2
RBM10
RBM14
RBM17
RBM4
RBM4B
RBM5
RTCA
RTCB
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
TUT4
TUT7
U2SURP
UPF1
UTP20
XAB2
YBX1
YBX2
YBX3
ZFR
ZNF106
ZNF346
Entrez ID
1477
406891
HPRD ID
02653
Ensembl ID
ENSG00000101138
ENSG00000199179
Uniprot IDs
Q05048
PDB IDs
6B3X
Enriched GO Terms of Interacting Partners
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