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CMTM4 and APOA4
Data Source:
BioGRID
(two hybrid)
CMTM4
APOA4
Description
CKLF like MARVEL transmembrane domain containing 4
apolipoprotein A4
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Extracellular Region
Extracellular Space
Early Endosome
Endoplasmic Reticulum Lumen
Cytosol
Cell Surface
Very-low-density Lipoprotein Particle
High-density Lipoprotein Particle
Chylomicron
Collagen-containing Extracellular Matrix
Extracellular Exosome
Blood Microparticle
Molecular Function
Protein Binding
Lipid Transporter Activity
Copper Ion Binding
Protein Binding
Phospholipid Binding
Lipid Binding
Cholesterol Binding
Antioxidant Activity
Phosphatidylcholine Binding
Identical Protein Binding
Protein Homodimerization Activity
Phosphatidylcholine-sterol O-acyltransferase Activator Activity
Cholesterol Transfer Activity
Biological Process
Retinoid Metabolic Process
Innate Immune Response In Mucosa
Cholesterol Biosynthetic Process
Lipid Transport
Response To Lipid Hydroperoxide
Leukocyte Cell-cell Adhesion
Cholesterol Metabolic Process
Positive Regulation Of Cholesterol Esterification
Positive Regulation Of Triglyceride Catabolic Process
Lipid Catabolic Process
Removal Of Superoxide Radicals
Regulation Of Intestinal Cholesterol Absorption
Regulation Of Cholesterol Transport
Cholesterol Efflux
Phospholipid Efflux
Chylomicron Remodeling
Very-low-density Lipoprotein Particle Remodeling
High-density Lipoprotein Particle Remodeling
Chylomicron Assembly
High-density Lipoprotein Particle Assembly
Negative Regulation Of Plasma Lipoprotein Oxidation
Response To Stilbenoid
Lipoprotein Metabolic Process
Cholesterol Homeostasis
Hydrogen Peroxide Catabolic Process
Reverse Cholesterol Transport
Cellular Protein Metabolic Process
Positive Regulation Of Fatty Acid Biosynthetic Process
Phosphatidylcholine Metabolic Process
Positive Regulation Of Lipid Biosynthetic Process
Positive Regulation Of Lipoprotein Lipase Activity
Lipid Homeostasis
Protein-lipid Complex Assembly
Triglyceride Homeostasis
Intermembrane Lipid Transfer
Pathways
Chylomicron assembly
Assembly of active LPL and LIPC lipase complexes
Chylomicron remodeling
Retinoid metabolism and transport
Retinoid metabolism and transport
Amyloid fiber formation
Drugs
Zinc
Copper
Zinc acetate
Diseases
GWAS
Apolipoprotein A-IV levels (
27412012
)
Body mass index (
31978080
)
Cholesterol, total (
19060911
20686565
)
Coronary artery disease (
29263402
)
Coronary heart disease (
21378990
)
Delirium (
29631748
)
Fasting triglyceride levels (
32603185
)
HDL cholesterol (
20864672
19060906
20686565
26582766
)
HDL cholesterol levels (
28334899
)
Hematological and biochemical traits (
20139978
)
Hypertriglyceridemia (
23505323
)
LDL cholesterol (
20864672
19060911
20686565
)
LDL cholesterol levels (
28334899
)
Lipid metabolism phenotypes (
22286219
)
Lipid traits (
24386095
)
Metabolic syndrome (
30382898
)
Metabolite levels (
22916037
)
Postprandial triglyceride levels (
32603185
)
Total cholesterol levels (
28334899
29403010
29615537
)
Triglyceride levels (
32203549
28334899
26763881
28371326
29615537
32335043
)
Triglycerides (
19074352
21909109
18193043
18193044
20864672
19060906
19060911
20139978
20686565
26582766
)
Interacting Genes
20 interacting genes:
APOA4
APPL1
COQ8A
DAPK1
DGCR6L
DIABLO
HSBP1L1
MIDN
MRPL2
PBX3
PTPN9
SMG9
SNX1
SPG21
SSX3
STAR
TBRG4
TCEA2
TTPA
ZFYVE21
5 interacting genes:
AGTRAP
CMTM4
CMTM5
GPLD1
MAGEA6
Entrez ID
146223
337
HPRD ID
07435
00130
Ensembl ID
ENSG00000183723
ENSG00000110244
Uniprot IDs
Q8IZR5
P06727
PDB IDs
3S84
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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