SPATA8 and GOPC

Data Source:
BioGRID (two hybrid)

		SPATA8	GOPC
Description		spermatogenesis associated 8	golgi associated PDZ and coiled-coil motif containing
Image		No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Trans-Golgi Network Transport Vesicle Dendrite Golgi-associated Vesicle Membrane Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Ion Channel Binding
	Biological Process		Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Negative Regulation Of Anion Channel Activity Protein Transport Cytoplasmic Sequestering Of CFTR Protein Apical Protein Localization Negative Regulation Of Protein Localization To Cell Surface
Pathways			RHO GTPases regulate CFTR trafficking
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Cerebrospinal fluid AB1-42 levels ( 26252872) Childhood ear infection ( 27182965 28928442) Chronotype ( 30696823) Cotinine glucuronidation ( 25293881) General risk tolerance (MTAG) ( 30643258) Health literacy ( 31250787) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Severe influenza A (H1N1) infection ( 26379185) Systemic lupus erythematosus ( 24871463)	Atrial fibrillation ( 29892015) Colorectal cancer ( 23266556) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Facial emotion recognition (fearful faces) ( 28608620) Night sleep phenotypes ( 27126917)
Interacting Genes		25 interacting genes: ADAMTSL4 CMTM5 COL8A1 CYSRT1 EFEMP2 FHL3 GOPC HNRNPF KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP6-2 KRTAP9-2 MDFI MKRN3 MLH1 MTUS2 NBPF19 NOTCH2NLA PLSCR1 PSMA3 RBPMS TEKT4 ZNF76	70 interacting genes: ABCA1 ADRB1 AKIRIN1 ASIC3 ATG9A BATF BECN1 C17orf67 CCDC102B CCDC198 CD300C CDKN2C CERCAM CFTR CLCN3 CRHR1 CSPG5 DLEU1 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GEM GOLGA3 GRID1 GRID2 HCK HNRNPLL IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MYLK MYOCD NOTCH1 NUP62 OSBP2 PARK7 PID1 PPP1R18 PWWP3A RALGAPB RELA RHOQ RNF183 RNF220 RPL13AP17 RPS6KA1 RTKN SEMA4G SLC25A18 SNX31 SPATA8 SSTR5 STARD3 STX6 TGFBR2 VIM VTN ZBTB49 ZDHHC1 ZNF564 ZNF581 ZNF587 ZNF835 ZSCAN1
Entrez ID		145946	57120
HPRD ID		15432	06024
Ensembl ID		ENSG00000185594	ENSG00000047932
Uniprot IDs			Q9HD26
PDB IDs			2DC2 2LOB 4E34 4E35 4JOE 4JOF 4JOG 4JOH 4JOJ 4JOK 4JOP 4JOR 4K6Y 4K72 4K75 4K76 4K78 4NMO 4NMP 4NMQ 4NMR 4NMS 4NMT 4NMV 4Q6H 4Q6S 5IC3 5K4F 6OV7 6XNJ
Enriched GO Terms of Interacting Partners?
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