TMCO5A and VAMP5

Data Source:
BioGRID (two hybrid)

		TMCO5A	VAMP5
Description		transmembrane and coiled-coil domains 5A	vesicle associated membrane protein 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Late Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Intercalated Disc Cytoplasmic Vesicle Membrane Integral Component Of Organelle Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Muscle Organ Development Skeletal Muscle Tissue Development Cell Differentiation Golgi To Plasma Membrane Protein Transport
Pathways
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Femoral neck bone mineral density ( 29499414) Gut microbiota (bacterial taxa) ( 27723756) Lumbar spine bone mineral density ( 29499414) Major depressive disorder ( 27479909) NASH resolution in nonalcoholic steatohepatitis ( 31832568) Total body bone mineral density ( 29304378) Urate levels in overweight individuals ( 25811787)	Coronary artery disease ( 29212778 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Myocardial infarction ( 26343387) Platelet distribution width ( 32888494) Prostate cancer ( 21743467) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		7 interacting genes: BET1 C1orf216 GOSR2 PRH1 TMEM60 TSPAN18 VAMP5	59 interacting genes: ABHD16A AQP6 ASGR2 ATP6AP2 BIK CD53 CLDN5 CLDN7 COMT CPLX4 CYB5R3 ELOVL4 FAM209A FNDC9 GJA8 GORAB GPR152 GPX8 GRAMD2B HIBADH IL3RA JAGN1 KIR2DL3 KIR3DL3 KLRC1 LMNA LRRC25 MDC1 MUC1 NCAPH2 PANX1 PLAC8 PVR RETREG3 SAR1A SLC14A2 SLC18A1 SNAP29 SPINT1 STX16 STX1A STX1B STX2 STX4 STX5 STX8 TAS2R5 TM4SF18 TMCO5A TMEM106C TMEM139 TMEM14B TMEM31 TMEM45B TMEM52B TMEM86B TMPRSS2 TMX2 VSIG4
Entrez ID		145942	10791
HPRD ID		11341	09513
Ensembl ID		ENSG00000166069	ENSG00000168899
Uniprot IDs		A0A024R9I9 Q8N6Q1	O95183 Q6FG93
PDB IDs
Enriched GO Terms of Interacting Partners?
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