CSNK1G3 and PPP1R14A

Data Source:
HPRD (in vitro)

		CSNK1G3	PPP1R14A
Description		casein kinase 1 gamma 3	protein phosphatase 1 regulatory inhibitor subunit 14A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Cytosol
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Serine/threonine Phosphatase Inhibitor Activity
	Biological Process	Cellular Protein Modification Process Endocytosis Signal Transduction Wnt Signaling Pathway Peptidyl-serine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway	Negative Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Phosphorylation
Pathways			RHO GTPases activate PKNs
Drugs		Purvalanol A {4-Amino-2-[(4-methoxyphenyl)amino]-1,3-thiazol-5-yl}(4-methoxyphenyl)methanone 4-Amino-2-[(3-chlorophenyl)amino]-5-(4-fluorobenzoyl)-1,3-thiazol-3-ium K-00546
Diseases
GWAS		Adult asthma ( 27611488) Amyotrophic lateral sclerosis ( 19451621) Apolipoprotein B levels ( 32203549) Cholesterol, total ( 24097068) Chronotype ( 30696823) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Diastolic blood pressure ( 27618452 30578418) Heel bone mineral density ( 30598549 28869591) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 32203549 28334899) Low density lipoprotein cholesterol levels ( 32154731) Metabolite levels ( 23823483) Nickel levels ( 26025379) Pulse pressure ( 27618448) Red cell distribution width ( 32888494) Systolic blood pressure ( 27618452) Total body bone mineral density ( 29304378) Total cholesterol levels ( 28334899) Virologic severity in Herpes simplex virus type 2 infection ( 29535370)	Diverticular disease ( 30177863)
Interacting Genes		5 interacting genes: DBNDD2 DRICH1 KRTAP10-10 MDFI PPP1R14A	16 interacting genes: APP CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 DAPK1 PRKCA PRKCE PRKCG PRKCH PRKCZ PRKD1 PRNP YWHAZ
Entrez ID		1456	94274
HPRD ID		05034	16291
Ensembl ID		ENSG00000151292	ENSG00000167641
Uniprot IDs		Q9Y6M4	Q96A00
PDB IDs		2CHL 2IZR 2IZS 2IZT 2IZU 4G16 4G17 4HGL 4HGS 6GRO
Enriched GO Terms of Interacting Partners?
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