RDH12 and PLEKHA7

Data Source:
BioGRID (two hybrid)

		RDH12	PLEKHA7
Description		retinol dehydrogenase 12	pleckstrin homology domain containing A7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Endoplasmic Reticulum Membrane Photoreceptor Inner Segment Membrane	Nucleoplasm Centrosome Cytosol Zonula Adherens Cell Junction Pore Complex Extracellular Exosome
	Molecular Function	Retinol Dehydrogenase Activity Protein Binding NADP-retinol Dehydrogenase Activity	Protein Binding Delta-catenin Binding
	Biological Process	Retinoid Metabolic Process Visual Perception Retinol Metabolic Process Photoreceptor Cell Maintenance Cellular Detoxification Of Aldehyde	Cell-cell Adhesion Mediated By Cadherin Zonula Adherens Maintenance Pore Complex Assembly Epithelial Cell-cell Adhesion
Pathways		Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision)
Drugs		Vitamin A
Diseases		Leber congenital amaurosis (LCR)
GWAS			Blood pressure ( 21909110) Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Coronary artery disease ( 29212778) Diastolic blood pressure ( 19430479 27841878 28739976 27618452) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Glaucoma (primary angle closure) ( 22922875 27064256) Intraocular pressure ( 29617998 29785010 31959993 30054594) Macular thickness ( 30535121) Mean arterial pressure ( 27618448) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Microalbuminuria in type 1 diabetes ( 31537649) Systolic blood pressure ( 19430479 27841878 28739976 27618452 30578418) Systolic blood pressure change trajectories ( 27980656) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		5 interacting genes: ANXA8L1 BUB1 MAP1LC3A PLEKHA7 RBPMS	20 interacting genes: B9D2 CCHCR1 CCNDBP1 FAM228A GRB2 HOMEZ HSF2BP IGFBP6 IGFL2 LZTS1 NEK6 PIBF1 PICK1 PPL RDH12 RHOH STMN3 TRAF4 TSGA10 ZMAT5
Entrez ID		145226	144100
HPRD ID		10585	15142
Ensembl ID		ENSG00000139988	ENSG00000166689
Uniprot IDs		A0A0S2Z613 Q96NR8	E9PKC0 Q6IQ23
PDB IDs
Enriched GO Terms of Interacting Partners?
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