DUSP19 and ZNF804A

Data Source:
BioGRID (biochemical)

		DUSP19	ZNF804A
Description		dual specificity phosphatase 19	zinc finger protein 804A
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Cytoplasm Plasma Membrane Growth Cone Neuronal Cell Body Dendritic Spine Dendritic Shaft Presynapse Postsynapse Dendritic Microtubule
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Kinase Inhibitor Activity MAP-kinase Scaffold Activity Protein Binding JUN Kinase Phosphatase Activity Protein Kinase Activator Activity Mitogen-activated Protein Kinase Kinase Kinase Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Molecular_function Metal Ion Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Activation Of Protein Kinase Activity Peptidyl-tyrosine Dephosphorylation Regulation Of MAP Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of JUN Kinase Activity Negative Regulation Of JUN Kinase Activity Positive Regulation Of Protein Kinase Activity Negative Regulation Of JNK Cascade Positive Regulation Of JNK Cascade	Positive Regulation Of Gene Expression Regulation Of Neuron Projection Development Positive Regulation Of Neuron Projection Development Positive Regulation Of Dendritic Spine Maintenance
Pathways
Drugs
Diseases
GWAS			Alzheimer disease and age of onset ( 26830138) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bipolar disorder ( 31043756) Bipolar disorder lithium response (continuous) or schizophrenia ( 29121268) Breakfast cereal skipping frequency ( 31190057) Breakfast skipping ( 31190057) Broad depression or schizophrenia ( 30626913) Cervical artery dissection ( 25420145) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Dentures ( 31235808) Feeling hurt ( 29500382) Loneliness (linear analysis) ( 27629369) Neurociticism ( 29500382) Neuroticism ( 29255261) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Obesity-related traits ( 23251661) Schizophrenia ( 28991256 25056061 18677311 29483656 30285260) Systolic blood pressure ( 30224653)
Interacting Genes		20 interacting genes: ACTB ALAS1 ALK EGFR EPHA2 EPHB6 ERBB2 ERBB3 ERBB4 FLT4 IGF1R INSR KDR LMTK2 MAP2K7 MAP3K5 MAPK9 PTK7 ROR1 ROR2	2 interacting genes: ATXN1 SPP1
Entrez ID		142679	91752
HPRD ID		13254	12804
Ensembl ID		ENSG00000162999	ENSG00000170396
Uniprot IDs		Q8WTR2	Q7Z570
PDB IDs		3S4E 4D3P 4D3Q 4D3R
Enriched GO Terms of Interacting Partners?
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