CRYBA2 and LASP1

Data Source:
BioGRID (two hybrid)

		CRYBA2	LASP1
Description		crystallin beta A2	LIM and SH3 protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Cytoplasm Focal Adhesion Cortical Actin Cytoskeleton
	Molecular Function	Molecular_function Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding	Protein Binding Ion Transmembrane Transporter Activity Cadherin Binding Metal Ion Binding Actin Filament Binding
	Biological Process	Lens Development In Camera-type Eye Visual Perception Biological_process	Ion Transport Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Height ( 31562340 18391951) Macular thickness ( 30535121) Neutrophil percentage of white cells ( 32888494) Systolic blood pressure ( 28234671) Type 2 diabetes (adjusted for BMI) ( 30297969)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)
Interacting Genes		27 interacting genes: ANAPC11 ARID5A BPIFA1 C10orf55 C22orf39 CALCOCO1 CCDC33 CRYBB1 CRYBB2 CRYBB3 CTDSP1 CYSRT1 FHL3 FHL5 KRTAP11-1 KRTAP13-3 KRTAP7-1 LASP1 NFKBID OXER1 PRR22 RUSC1 TRAF2 TRIP13 UNKL VAC14 YPEL3	121 interacting genes: ACD ACTA1 ACTB ACTC1 ANKS1A ARHGEF15 ARHGEF16 ARID5A ATXN1 BAG4 BAHD1 BHLHE40 C14orf119 C19orf54 CAMK2A CATSPER1 CDK7 CERCAM CHERP COPS5 CRK CRYBA1 CRYBA2 CSTF2T CTNNA3 CYSRT1 DAZAP2 DMRT3 DNMT1 DOK6 DTX2 EHMT2 EVX2 FAM168A FAM168B FBXO17 FHL3 FOXH1 FXR2 GAS8 GCM2 GOLGA2 GUCD1 HGS HNRNPF HOXA1 INTS11 KRTAP10-8 KRTAP12-4 KRTAP19-3 KRTAP19-4 KRTAP19-6 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP6-2 LENG8 LMO4 LZTS2 MDFI MED25 MGAT5B MKRN3 NOXA1 NUTF2 OTX1 OXER1 PITX1 PLSCR1 POLD1 POT1 POU1F1 PPP1R32 PRKAR2B PRKG1 PRKG2 PRR20A PRR20B PRR20C PRR20D PRR20E PRR35 PSMA3 QRICH1 RBFOX1 RBPMS RBPMS2 REL RHOXF2 RNF38 SEPTIN3 SPAG8 SPRY2 STAT3 TCF4 TEKT3 TEKT4 TEKT5 TERF1 TFG THAP1 TINF2 TLX3 TNS2 TRIM27 TRIP13 UBQLN2 UFSP1 UHRF1 VAC14 VEZF1 VGLL3 VPS37C WWOX YES1 YTHDF1 ZBTB9 ZC2HC1A ZC3H10 ZYX
Entrez ID		1412	3927
HPRD ID		02905	04229
Ensembl ID		ENSG00000163499	ENSG00000002834
Uniprot IDs		A0A024R429 P53672	A0A024R1S8 B4DIC4 Q14847
PDB IDs			3I35
Enriched GO Terms of Interacting Partners?
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