OTUD6A and EMX2

Data Source:
BioGRID (two hybrid)

		OTUD6A	EMX2
Description		OTU deubiquitinase 6A	empty spiracles homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation Protein K29-linked Deubiquitination Protein K11-linked Deubiquitination Protein K27-linked Deubiquitination Protein K33-linked Deubiquitination	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Brain Development Anterior/posterior Pattern Specification Dentate Gyrus Development Cerebral Cortex Regionalization Cell Proliferation In Forebrain Forebrain Cell Migration Neuron Differentiation Response To Drug Ureter Morphogenesis
Pathways
Drugs
Diseases
GWAS			Airflow obstruction ( 22837378) Celiac disease ( 23936387) Chronotype ( 30696823) Double-edged eyelids ( 29895819) Early cardiac repolarization ( 22683750) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Liver fibrosis (total hepatic collagen content) ( 32953199) Low tan response ( 29739929) Neuroticism ( 29255261) Obesity-related traits ( 23251661) Ovarian disease with few adhesions ( 28333195) Photic sneeze reflex ( 27182965) Pulmonary function in asthmatics ( 23541324) Response to quetiapine in schizophrenia ( 29503163) Serum uric acid levels ( 30993211 29403010) Skin pigmentation ( 30664655) Skin, hair and eye pigmentation (multivariate analysis) ( 30664655) Urate levels ( 31578528)
Interacting Genes		18 interacting genes: CBLC DPYSL3 DYNLL1 DYNLL2 EMX2 MYCL NUP62 PDLIM7 POM121 RBCK1 RNF2 SSBP1 TRIM39 TRIM46 TRIM5 TRIM7 UBC VPS52	5 interacting genes: EIF4E GTF2A1L MEIS1 OTUD6A TLE2
Entrez ID		139562	2018
HPRD ID		13681	02495
Ensembl ID		ENSG00000189401	ENSG00000170370
Uniprot IDs		Q7L8S5	Q04743
PDB IDs
Enriched GO Terms of Interacting Partners?
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