COX5B and ARID5A

Data Source:
BioGRID (two hybrid)

		COX5B	ARID5A
Description		cytochrome c oxidase subunit 5B	AT-rich interaction domain 5A
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding Metal Ion Binding	Transcription Regulatory Region Sequence-specific DNA Binding DNA Binding Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding Estrogen Receptor Binding Identical Protein Binding Sequence-specific DNA Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding Androgen Receptor Binding
	Biological Process	Mitochondrial Electron Transport, Cytochrome C To Oxygen Respiratory Gaseous Exchange By Respiratory System	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Innate Immune Response Negative Regulation Of Transcription, DNA-templated Cellular Response To Estrogen Stimulus
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport
Drugs		Cholic Acid N-Formylmethionine
Diseases
GWAS		Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Event-related brain oscillations ( 21184583)
Interacting Genes		35 interacting genes: AR ARID5A BHLHE40 CDC42EP2 CDR2 CDR2L DOK3 FAM228A FLOT1 GOLGA2 IHO1 KRT15 KRT27 KRT31 KRT33B LSM4 MCCD1 MID2 NUDT5 OIP5 PLEKHF2 PNMA1 PPP1R32 PRDM6 PRKAR1B PRR22 RBM48 SLAIN1 TASOR2 TEX12 TFIP11 TRAF1 TRIM23 TRIM27 VPS28	127 interacting genes: ANKRD11 AR ATP6V0D2 ATXN1 ATXN1L BAG4 BAHD1 BANP BOLL C14orf119 C19orf54 CAMK2A CATSPER1 CCDC120 CCDC57 CKS1B COX5B CRYBA1 CRYBA2 CYSRT1 DAB1 DAZAP2 DOK6 DTX2 ESR2 ESRP1 FAM168B FHL3 FOXD2 FOXH1 GATA5 GLIS2 GOLGA2 GRB2 HDAC7 HOXA1 HSD3B7 INIP IRX6 KAZN KCTD9 KDF1 KRT40 KRTAP10-8 KRTAP12-2 KRTAP12-4 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP22-1 KRTAP26-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LASP1 LENG8 LIMS3 LIMS4 LITAF LMO2 MAB21L2 MAGED1 MDFI MIEN1 MKRN3 MORN3 MYLIP NUDT22 ODAM OLIG3 OTX1 PHF1 PIBF1 PIN1 PITX1 PLA2G10 PLAGL2 PLEKHN1 PNMA1 POU1F1 PRDM6 PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RARA RBFOX1 RBPMS RBPMS2 RFC5 RHOXF2 RNF44 ROR2 RXRA SEC24A SH2D2A SMYD1 SOHLH1 SOX5 TEKT3 TEKT4 TENT5A TENT5D TGM7 THRA TNS2 TRAF1 TRIM27 TRIM73 TSC1 TSEN15 TSSK3 UBTD2 USP20 VAC14 VENTX ZC3H10 ZIC1 ZNF503 ZNF765
Entrez ID		1329	10865
HPRD ID		00467	12481
Ensembl ID		ENSG00000135940	ENSG00000196843
Uniprot IDs		A0A384NL93 P10606	Q03989
PDB IDs		5Z62
Enriched GO Terms of Interacting Partners?
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