MAP3K8 and LYZL2

		MAP3K8	LYZL2
Description		mitogen-activated protein kinase kinase kinase 8	lysozyme like 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Extracellular Region
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding	Lysozyme Activity
	Biological Process	Activation Of MAPKK Activity Protein Phosphorylation Cell Cycle T Cell Costimulation Stress-activated MAPK Cascade Interleukin-1-mediated Signaling Pathway	Metabolic Process
Pathways		CD28 dependent PI3K/Akt signaling MAP3K8 (TPL2)-dependent MAPK1/3 activation MAP3K8 (TPL2)-dependent MAPK1/3 activation
Drugs
Diseases
GWAS		Asthma ( 32296059) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Systemising ( 31508503) Ulcerative colitis ( 28067908)	Bone mineral density (femoral neck) ( 26911590) Dental caries ( 23064961)
Interacting Genes		17 interacting genes: ACY3 AKT1 BMPR2 CD40 CHUK MAP2K1 MAP2K4 MAP3K14 NFKB1 NFKB2 REL RELA RIPK1 STIP1 TNIP2 TRAF2 TRAF6
Entrez ID		1326	119180
HPRD ID		01863	14337
Ensembl ID		ENSG00000107968	ENSG00000151033
Uniprot IDs		P41279 Q6FG25	A0A080YUZ9 Q7Z4W2
PDB IDs		4Y83 4Y85 5IU2
Enriched GO Terms of Interacting Partners?
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