CPNE4 and CCDC22

Data Source:
HPRD (two hybrid, in vitro)

		CPNE4	CCDC22
Description		copine 4	coiled-coil domain containing 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Extracellular Exosome	Cellular_component Nucleoplasm Endosome Cytosol
	Molecular Function	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding	Protein Binding Cullin Family Protein Binding
	Biological Process	Cellular Response To Calcium Ion	Cellular Copper Ion Homeostasis Golgi To Plasma Membrane Transport Cytoplasmic Sequestering Of NF-kappaB Protein Transport Protein Ubiquitination Endocytic Recycling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Post-translational Protein Modification Retrograde Transport, Endosome To Plasma Membrane Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways			Neddylation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Amyotrophic lateral sclerosis ( 22959728) Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals ( 22959728) Body mass index ( 31453325 28892062 25673413) Body mass index variance ( 31453325) Body size at age 10 ( 32376654) Circulating leptin levels in high cardiovascular risk ( 31766143) Coronary artery aneurysm in Kawasaki disease ( 27171184) HDL cholesterol levels ( 32203549) Intracranial aneurysm ( 29531279) Iron status biomarkers (total iron binding capacity) ( 28334935) Metabolic syndrome ( 31589552) Motion sickness ( 25628336) Neutrophil count ( 21507922)	Vitiligo ( 27723757)
Interacting Genes		17 interacting genes: ACTB BCOR BICD1 CCDC22 CEP162 CPNE1 MAP2K1 MYCBP NECAB1 PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 UBE2M UBE2O	8 interacting genes: ACTG1 ARSA BLOC1S6 CPNE1 CPNE4 KRT27 OIP5 USHBP1
Entrez ID		131034	28952
HPRD ID		05017	06594
Ensembl ID		ENSG00000196353	ENSG00000101997
Uniprot IDs		B7Z370 Q4G168 Q96A23	A0A024QZ03 O60826
PDB IDs
Enriched GO Terms of Interacting Partners?
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