UBR3 and BBS5

Data Source:
HPRD (in vivo)

		UBR3	BBS5
Description		ubiquitin protein ligase E3 component n-recognin 3	Bardet-Biedl syndrome 5
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Integral Component Of Membrane	Cytosol Axoneme Centriolar Satellite BBSome Ciliary Basal Body Ciliary Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding Phosphatidylinositol-3-phosphate Binding
	Biological Process	Suckling Behavior Ubiquitin-dependent Protein Catabolic Process Sensory Perception Of Smell Embryo Development Ending In Birth Or Egg Hatching Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway	Heart Looping Visual Perception Protein Transport Melanosome Transport Motile Cilium Assembly Intracellular Transport Response To Stimulus Cilium Assembly
Pathways			BBSome-mediated cargo-targeting to cilium
Drugs
Diseases			Bardet-Biedl syndrome (BBS)
GWAS		Longitudinal change in brain amyloid plaque burden ( 26268530) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Urate levels in obese individuals ( 25811787)	Iris heterochromicity ( 30895295)
Interacting Genes		7 interacting genes: APEX1 DZIP3 MAGEC2 UBE2A UBE2B UBE2D2 UBE2H	2 interacting genes: CRADD KLC3
Entrez ID		130507	129880
HPRD ID		15887	10353
Ensembl ID		ENSG00000144357	ENSG00000163093
Uniprot IDs		Q6ZT12	A0A0S2Z626 Q8N3I7
PDB IDs			6XTB
Enriched GO Terms of Interacting Partners?
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