ADH6 and ANKRD17

Data Source:
BioGRID (two hybrid)

		ADH6	ANKRD17
Description		alcohol dehydrogenase 6 (class V)	ankyrin repeat domain 17
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Chromatin Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Membrane
	Molecular Function	Alcohol Dehydrogenase (NAD+) Activity Alcohol Dehydrogenase Activity, Zinc-dependent Retinol Dehydrogenase Activity Zinc Ion Binding	Chromatin Binding RNA Binding Protein Binding
	Biological Process	Ethanol Oxidation Retinol Metabolic Process Retinoic Acid Metabolic Process Response To Ethanol	Blood Vessel Maturation Regulation Of DNA Replication Viral Process Defense Response To Bacterium Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Cell Cycle Negative Regulation Of Smooth Muscle Cell Differentiation Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway
Pathways		Ethanol oxidation
Drugs
Diseases
GWAS		Alcohol dependence ( 23456092) Alcohol use disorder (consumption score) ( 30940813 30336701) Alcohol use disorder (dependence and problematic use scores) ( 30336701) Esophageal cancer ( 19698717) QRS duration ( 23534349) Regular attendance at a pub or social club ( 29970889)	Apolipoprotein B levels ( 32203549) Cholesterol ester levels in large LDL ( 29084231) Cholesterol ester levels in medium LDL ( 29084231) Esterified cholesterol levels ( 29084231) Free cholesterol levels in large LDL ( 29084231) Hematocrit ( 32888494) Large LDL particle concentration ( 29084231) Medium LDL particle concentration ( 29084231) Prostate cancer ( 23535732) Red blood cell count ( 32888494) Smooth-surface caries ( 24556642) Total cholesterol levels in large LDL ( 29084231) Total cholesterol levels in medium LDL ( 29084231) Total cholesterol levels in small LDL ( 29084231)
Interacting Genes		8 interacting genes: ANKRD17 ARRB1 KRAS RASSF5 RPAIN RPS29 RSL1D1 TNIP1	5 interacting genes: ADH6 APC ECPAS ITSN2 MDM2
Entrez ID		130	26057
HPRD ID		00067	10648
Ensembl ID		ENSG00000172955	ENSG00000132466
Uniprot IDs		P28332 Q8IUN7	O75179
PDB IDs
Enriched GO Terms of Interacting Partners?
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