BBS5 and UBR3

Data Source:
HPRD (in vivo)

		BBS5	UBR3
Description		Bardet-Biedl syndrome 5	ubiquitin protein ligase E3 component n-recognin 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Axoneme Centriolar Satellite BBSome Ciliary Basal Body Ciliary Membrane	Ubiquitin Ligase Complex Cytoplasm Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding Phosphatidylinositol-3-phosphate Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Heart Looping Visual Perception Protein Transport Melanosome Transport Motile Cilium Assembly Intracellular Transport Response To Stimulus Cilium Assembly	Suckling Behavior Ubiquitin-dependent Protein Catabolic Process Sensory Perception Of Smell Embryo Development Ending In Birth Or Egg Hatching Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway
Pathways		BBSome-mediated cargo-targeting to cilium
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS		Iris heterochromicity ( 30895295)	Longitudinal change in brain amyloid plaque burden ( 26268530) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Urate levels in obese individuals ( 25811787)
Interacting Genes		2 interacting genes: CRADD KLC3	7 interacting genes: APEX1 DZIP3 MAGEC2 UBE2A UBE2B UBE2D2 UBE2H
Entrez ID		129880	130507
HPRD ID		10353	15887
Ensembl ID		ENSG00000163093	ENSG00000144357
Uniprot IDs		A0A0S2Z626 Q8N3I7	Q6ZT12
PDB IDs		6XTB
Enriched GO Terms of Interacting Partners?
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