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IQGAP3 and CCDC198
Data Source:
BioGRID
(two hybrid)
IQGAP3
CCDC198
Description
IQ motif containing GTPase activating protein 3
coiled-coil domain containing 198
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Cell-cell Junction
Lateral Plasma Membrane
Molecular Function
GTPase Activator Activity
Protein Binding
Calmodulin Binding
Actin Filament Binding
Myosin VI Light Chain Binding
Protein Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Activation Of MAPK Activity
Ras Protein Signal Transduction
Regulation Of Cell Size
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Regulation Of Actin Cytoskeleton Organization
Positive Regulation Of Mammary Gland Epithelial Cell Proliferation
Positive Regulation Of GTPase Activity
ERK1 And ERK2 Cascade
Cellular Response To Organic Substance
Pathways
RHO GTPases activate IQGAPs
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Creatine kinase levels (
29403010
)
Interacting Genes
2 interacting genes:
CALM2
CCDC198
27 interacting genes:
CBY2
FAM9B
FHL2
FHL3
FKBP6
GOLGA2
GOPC
HOOK2
HSF2BP
IQGAP3
KIFC3
KRT31
KRT34
KRT40
LZTS2
MDFI
MTUS2
PDE4DIP
PFDN5
PNMA1
SIAH1
SMAD3
SSX2IP
TEX11
TRAF1
TRAF2
TRIM27
Entrez ID
128239
55195
HPRD ID
11051
12628
Ensembl ID
ENSG00000183856
ENSG00000100557
Uniprot IDs
Q86VI3
B7ZL43
E9PSE9
F5GWJ3
Q05C89
Q9NVL8
PDB IDs
3ISU
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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