ADH5 and SLC66A2

Data Source:
BioGRID (two hybrid)

		ADH5	SLC66A2
Description		alcohol dehydrogenase 5 (class III), chi polypeptide	solute carrier family 66 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Extracellular Exosome	Endosome Trans-Golgi Network Cytosol Integral Component Of Membrane
	Molecular Function	Alcohol Dehydrogenase Activity, Zinc-dependent Fatty Acid Binding Zinc Ion Binding Electron Transfer Activity Formaldehyde Dehydrogenase Activity Identical Protein Binding S-(hydroxymethyl)glutathione Dehydrogenase Activity S-(hydroxymethyl)glutathione Dehydrogenase NADP Activity S-(hydroxymethyl)glutathione Dehydrogenase NAD Activity	Protein Binding
	Biological Process	Retinoid Metabolic Process Respiratory System Process Ethanol Oxidation Fatty Acid Omega-oxidation Peptidyl-cysteine S-nitrosylation Electron Transport Chain Response To Lipopolysaccharide Positive Regulation Of Blood Pressure Formaldehyde Catabolic Process Response To Nitrosative Stress Response To Redox State	Retrograde Transport, Endosome To Golgi Phospholipid Translocation
Pathways		Ethanol oxidation
Drugs		NADH Lauric acid 12-Hydroxydodecanoic Acid S-Hydroxymethyl Glutathione
Diseases
GWAS		Alcohol consumption ( 28937693) Alcohol consumption in current drinkers ( 28937693) Alcohol dependence ( 23456092) Blood protein levels ( 30072576) HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899) Obesity-related traits ( 23251661) Plateletcrit ( 32888494) Regular attendance at a pub or social club ( 29970889)
Interacting Genes		9 interacting genes: APP ARNT CHD3 CSNK2B ESRRA PRDX1 SLC66A2 SNTA1 VTN	24 interacting genes: ADH5 AQP6 BEST2 CD79A CLCN7 DIABLO FBLN1 FUNDC2 GJA8 GPR152 IL10RA KCNK5 MFSD14B MGLL RHBDD1 SLC10A1 SLC10A6 SLC25A46 SLC35E3 STX12 TMEM31 TMEM44 TMEM80 ZFYVE27
Entrez ID		128	80148
HPRD ID		00064	11454
Ensembl ID		ENSG00000197894	ENSG00000122490
Uniprot IDs		P11766 Q6IRT1	Q8N2U9
PDB IDs		1M6H 1M6W 1MA0 1MC5 1MP0 1TEH 2FZE 2FZW 3QJ5
Enriched GO Terms of Interacting Partners?
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