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C1orf216 and ABI2
Data Source:
BioGRID
(two hybrid)
C1orf216
ABI2
Description
chromosome 1 open reading frame 216
abl interactor 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Adherens Junction
Lamellipodium
SCAR Complex
Filopodium Tip
Dendritic Spine
Molecular Function
Protein Binding
Protein Binding
Cytoskeletal Anchor Activity
SH3 Domain Binding
Kinase Binding
Small GTPase Binding
Ubiquitin Protein Ligase Binding
Signaling Adaptor Activity
Identical Protein Binding
Proline-rich Region Binding
Biological Process
Cytoskeleton Organization
Nervous System Development
Actin Polymerization Or Depolymerization
Positive Regulation Of Lamellipodium Assembly
Viral Process
Cell Migration
Rac Protein Signal Transduction
Peptidyl-tyrosine Phosphorylation
Regulation Of Dendritic Spine Morphogenesis
Lens Fiber Cell Morphogenesis
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) (
28090653
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Butyrylcholinesterase levels (
21862451
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Diverticular disease (
30177863
)
Subclinical atherosclerosis traits (other) (
17903303
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Trunk fat mass (
28552196
)
Urinary albumin-to-creatinine ratio (
31511532
)
Interacting Genes
71 interacting genes:
ABI2
AIMP2
AMOT
BORCS6
CCDC136
CCDC158
CCDC197
CDR2
CDR2L
CENPH
CEP170P1
CEP55
CMC2
DES
DMAP1
EIF3F
EXOC5
FSD2
GGA1
HAP1
HAUS8
IFT20
KLHL20
KRT13
KRT15
KRT16
KRT24
KRT27
KRT31
KRT33B
KRT34
KRT36
KRT38
KRT39
KRT40
KRT75
KRT76
LRRC61
MAGEA6
MDFI
MED4
MIS18A
MLPH
MRFAP1L1
MTUS2
MYRIP
NECAB2
NMI
NRBF2
NUP62
ODAD1
PKNOX2
PPP1R16A
PSMC6
RALBP1
SERTAD3
SNW1
SYCE1L
THAP1
TLE5
TMCO5A
TPM1
TPM3
TRAF1
TRIM54
TRIM72
USHBP1
VPS52
WASHC1
ZDHHC17
ZNF620
197 interacting genes:
ABI1
ABI3
ABL1
ABL2
ABLIM3
ADAM19
AKAP8L
AKAP9
ANKRD55
ANKS1A
ARHGAP32
ARMC7
ATP23
BAG4
BIN3
BLOC1S5
BLOC1S6
BORCS6
C19orf54
C1orf109
C1orf216
C20orf202
C4orf17
CCDC102B
CCDC115
CCDC57
CCDC74B
CCHCR1
CDK6
CENPH
CENPQ
CEP44
CEP57
CLPP
COG3
CRX
CUEDC1
DCTN2
DISC1
DLGAP2
DLGAP4
DNAI7
DTNB
EFS
EGLN3
EGR4
EIF3H
ENAH
ENKD1
EPS8L1
FAM161B
FAM166B
FAM214B
FAM90A1
FAM9C
FBXL19
FHL5
FKBP1A
FOXD4L1
GAS2L2
GCC1
GFAP
GGN
GPANK1
HGS
HHEX
HNRNPK
HOMER3
HSF2BP
IFT20
IHO1
INCA1
INO80B
INSYN1
KHDRBS1
KIAA1217
KIFC3
KNSTRN
KRT13
KRT14
KRT15
KRT19
KRT20
KRT24
KRT27
KRT31
KRT33B
KRT34
KRT36
KRT75
LENG1
LGALS9B
LHX3
LHX8
LMO1
LMO2
LMO3
LMO4
LNX1
LURAP1
LZTS2
MAGEA1
MCM7
MED10
MED11
MED29
MEOX2
MRFAP1
MRFAP1L1
MRPL28
MRPL44
MYO15B
MYOG
MYOZ3
NCK1
NCK2
NCKIPSD
NFASC
NHSL2
NME4
NUP62
OIP5
OOEP
PAK2
PCM1
PDLIM7
PFDN5
PHETA1
PHF1
PIN1
PLEKHN1
POMC
PPIF
PPP3CA
PRAM1
PRDM14
PRDM6
PRKAA1
PRKAA2
PRR16
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMA1
PWWP2B
RABEP1
RABGEF1
RASD1
RNPS1
RPP25
RSPH14
RUSC1
SCGN
SDCBP
SH3BP1
SH3KBP1
SLA
SMARCB1
SMARCD1
SNAP23
SNAP91
SNAPIN
SNX18
SNX7
SORBS3
STAM2
STX19
STX4
TFIP11
TLE5
TPM2
TRAF3IP1
TRIM32
TRIM72
TRIML2
TRIP6
UBQLN2
USHBP1
USP2
VARS2
VASP
VCL
VPS28
VPS37C
WASF2
WASF3
WASHC1
WASHC3
WASL
WIPF1
WWOX
ZFP90
ZMYND12
ZNF474
ZNF688
Entrez ID
127703
10152
HPRD ID
08798
07338
Ensembl ID
ENSG00000142686
ENSG00000138443
Uniprot IDs
Q8TAB5
A0A0C4DG21
A0A7D9NKC8
B7Z836
F8WAL6
Q9NYB9
PDB IDs
2ED0
3P8C
4N78
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Intersection)
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