ZNF648 and KRTAP12-3

Data Source:
BioGRID (two hybrid)

		ZNF648	KRTAP12-3
Description		zinc finger protein 648	keratin associated protein 12-3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytosol Keratin Filament
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II	Keratinization
Pathways			Keratinization
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Cardiovascular heart disease in diabetics ( 23982368) HDL cholesterol ( 24097068 25961943 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Morning person ( 30696823) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
Interacting Genes		61 interacting genes: AXIN2 BEGAIN BICD2 CALCOCO2 CARD14 CCDC120 CCDC136 CCDC57 CDR2L CEP70 CYSRT1 DVL3 EVI5L FSD2 GOLGA2 GOLGA6L9 HAP1 HOOK2 HSF2BP KANK2 KRTAP1-1 KRTAP10-8 KRTAP12-3 LDOC1 LZTS2 MCC MDFI MEOX2 MID2 MTUS2 NBPF19 NOTCH2NLA NUDT22 OSBPL3 PLEKHG4 RBAK RINT1 RUBCN SSX2IP SYNE4 TEX19 TNS2 TRAF1 TRAF2 TRIM41 ZBTB8A ZCCHC13 ZNF250 ZNF260 ZNF275 ZNF317 ZNF343 ZNF438 ZNF552 ZNF620 ZNF655 ZNF71 ZNF768 ZNF792 ZNF837 ZRANB1	142 interacting genes: ADAMTSL3 ADAMTSL4 AGXT ALDH3B1 BCL6B BMP7 C11orf87 C22orf39 CARD10 CATSPER1 CBX2 CELF5 CHIC2 CHRD CHRNG CNNM3 COL8A1 CRCT1 CREB5 CYSRT1 DALRD3 DHRS1 DHX57 DNAL4 DOCK2 FASLG FBXW5 GLRX3 GNE GTF3C5 HOXA1 ITGB4 JOSD1 KPRP KRT20 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP13-1 KRTAP13-2 KRTAP13-3 KRTAP19-7 KRTAP3-3 KRTAP4-2 KRTAP4-4 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP9-2 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LIF LMNTD2 LNX1 LYVE1 MAPKBP1 MEOX2 MISP MOBP NBPF19 NKD1 NMU NOTCH2NLA NPDC1 NR1D2 NR4A3 NUFIP2 OTX1 OXER1 P2RX4 P2RY6 P3H3 P4HB PDE9A PDGFRB PGAP6 PHLDA1 POU4F2 PTGDS PTPMT1 R3HDM2 RSPO2 SELENOM SHFL SLC13A5 SLC15A2 SLC23A1 SPATA3 SPRY1 TCEA2 TCEANC TFAP2D TMIE TNP2 TNS2 TTPA UTP23 UXT VASN VGLL3 VSTM4 WDR25 WNT11 YY1 ZDHHC1 ZNF101 ZNF124 ZNF138 ZNF20 ZNF408 ZNF417 ZNF439 ZNF440 ZNF467 ZNF490 ZNF491 ZNF497 ZNF578 ZNF587 ZNF648 ZNF696 ZNF80 ZNF835 ZNF837 ZSCAN21
Entrez ID		127665	386683
HPRD ID		18361	11199
Ensembl ID		ENSG00000179930	ENSG00000205439
Uniprot IDs		Q5T619	P60328
PDB IDs
Enriched GO Terms of Interacting Partners?
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