ATXN7L2 and SH3RF2

Data Source:
BioGRID (two hybrid)

		ATXN7L2	SH3RF2
Description		ataxin 7 like 2	SH3 domain containing ring finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm
	Molecular Function		Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Phosphatase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		Negative Regulation Of Phosphatase Activity Positive Regulation Of Cell Migration Negative Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Apoptotic Process Negative Regulation Of JNK Cascade Positive Regulation Of JNK Cascade Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 20125088)	Bacteremia ( 27236921) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Response to (pegylated) interferon in HBeAG-positive hepatitis B ( 30715261)
Interacting Genes		27 interacting genes: BAG3 BANP CBX1 CBX3 CTIF CYSRT1 FSD2 GOLGA6L9 HSF2BP HSPB8 IKZF3 KCTD7 KRT31 LAMB1 MB21D2 MDFI PACSIN3 PPP1R16A PPP2R3A PRDM6 RBPMS SBK3 SH3RF1 SH3RF2 SSC4D USP54 ZNF526	23 interacting genes: AKAP8L AMOTL2 APP ATXN7L2 BAG4 BANP CBY2 CCDC102B CYSRT1 EFS FASLG GOLGA2 HOMEZ LMNA LZTS2 MTUS2 NEK6 PAK4 PPP1CA PPP1CC RBPMS UBE2N VPS37C
Entrez ID		127002	153769
HPRD ID		12506	10229
Ensembl ID		ENSG00000162650	ENSG00000156463
Uniprot IDs		Q5T6C5	Q08AM8 Q8TEC5
PDB IDs
Enriched GO Terms of Interacting Partners?
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