ZSWIM7 and UQCRB

Data Source:
BioGRID (two hybrid)

		ZSWIM7	UQCRB
Description		zinc finger SWIM-type containing 7	ubiquinol-cytochrome c reductase binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Shu Complex	Mitochondrial Inner Membrane Mitochondrial Respirasome Mitochondrial Respiratory Chain Complex III
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Protein Stabilization	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration
Pathways			Respiratory electron transport
Drugs			2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Blood pressure (smoking interaction) ( 25189868)	Huntington's disease progression ( 28642124)
Interacting Genes		4 interacting genes: RAD51D SWSAP1 UQCRB XRCC3	9 interacting genes: ACAP1 ACCS HPCA HSPB1 LRRK2 MAGEA1 MAGEA4 MAGEB4 ZSWIM7
Entrez ID		125150	7381
HPRD ID		19095	11770
Ensembl ID		ENSG00000214941	ENSG00000156467
Uniprot IDs		A0A024RD64 Q19AV6	P14927
PDB IDs			5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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