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SNX20 and NFATC3
Data Source:
BioGRID
(affinity chromatography technology)
SNX20
NFATC3
Description
sorting nexin 20
nuclear factor of activated T cells 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Plasma Membrane
Early Endosome Membrane
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Cytosol
Molecular Function
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Phosphatidylinositol-3-phosphate Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Transcription Factor Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Protein Transport
Cytokine Production
Regulation Of Transcription By RNA Polymerase II
Inflammatory Response
Multicellular Organism Development
Calcineurin-NFAT Signaling Cascade
Fc-epsilon Receptor Signaling Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Pathways
Calcineurin activates NFAT
Calcineurin activates NFAT
FCERI mediated Ca+2 mobilization
CLEC7A (Dectin-1) induces NFAT activation
Drugs
Diseases
GWAS
Asthma (childhood onset) (
31036433
)
Crohn's disease (
28008999
28067908
22412388
)
Inflammatory bowel disease (
28008999
28067908
)
Chronotype (
30696823
)
Estimated glomerular filtration rate (
31015462
)
Refractive error (
32231278
)
Schizophrenia (
25056061
29483656
)
Urate levels (
31578528
)
Interacting Genes
8 interacting genes:
ALAS1
FAM9B
GMCL1
KLHL12
MAGEA11
SPDEF
TACC3
TFIP11
6 interacting genes:
CDK6
CSNK1A1
FOS
MAPK8
MAPK9
TTF1
Entrez ID
124460
4775
HPRD ID
15401
04077
Ensembl ID
ENSG00000167208
ENSG00000072736
Uniprot IDs
Q7Z614
B5B2S0
B5B2S1
Q12968
PDB IDs
2XRW
2XS0
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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