PLD4 and TRMT61A

Data Source:
BioGRID (two hybrid)

		PLD4	TRMT61A
Description		phospholipase D family member 4	tRNA methyltransferase 61A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Trans-Golgi Network Membrane Phagocytic Vesicle	Nucleus Nucleoplasm TRNA (m1A) Methyltransferase Complex
	Molecular Function	Phospholipase D Activity Single-stranded DNA 5'-3' Exodeoxyribonuclease Activity	Protein Binding TRNA (adenine-N1-)-methyltransferase Activity MRNA (adenine-N1-)-methyltransferase Activity
	Biological Process	Hematopoietic Progenitor Cell Differentiation DNA Metabolic Process Phagocytosis Inflammatory Response Inositol Phosphate Metabolic Process Innate Immune Response Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Cytokine Production Involved In Inflammatory Response	TRNA Modification TRNA Methylation MRNA Methylation
Pathways		Synthesis of PG Synthesis of IP3 and IP4 in the cytosol Role of phospholipids in phagocytosis	tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau levels ( 29274321) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Rheumatoid arthritis ( 30423114 22446963 24390342)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Branched-chain amino acid levels (Isoleucine) ( 27898682) Extremely high intelligence ( 29520040) Hemoglobin levels ( 32327693) Intelligence (MTAG) ( 29326435) Mean corpuscular volume ( 32888494 27863252) Red blood cell count ( 32888494) Schizophrenia ( 25056061)
Interacting Genes			2 interacting genes: TCL1A TRMT6
Entrez ID		122618	115708
HPRD ID		11230	08810
Ensembl ID		ENSG00000166428	ENSG00000166166
Uniprot IDs		A0A3B3IT68 B4DI07 B4DJQ6 F5H2B5 Q96BZ4	A0A024R6Q2 Q96FX7
PDB IDs			5CCB 5CCX 5CD1
Enriched GO Terms of Interacting Partners?
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