JAML and ADAMTS1

Data Source:
BioGRID (genetic interference)

		JAML	ADAMTS1
Description		junction adhesion molecule like	ADAM metallopeptidase with thrombospondin type 1 motif 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane	Basement Membrane Extracellular Matrix Cytoplasmic Vesicle Collagen-containing Extracellular Matrix
	Molecular Function	Integrin Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding	Metalloendopeptidase Activity Protein Binding Heparin Binding Metallopeptidase Activity Zinc Ion Binding
	Biological Process	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Neutrophil Chemotaxis Monocyte Extravasation Gamma-delta T Cell Activation Regulation Of Immune Response Leukocyte Migration Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Neutrophil Extravasation	Ovulation From Ovarian Follicle Kidney Development Proteolysis Integrin-mediated Signaling Pathway Negative Regulation Of Cell Population Proliferation Negative Regulation Of Angiogenesis Extracellular Matrix Organization Heart Trabecula Formation Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall	Degradation of the extracellular matrix Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS		Sleep duration (long sleep) ( 30846698)	Alzheimer's disease (late onset) ( 30820047) Blood protein levels ( 28240269) Cerebrospinal fluid neurofilament light levels ( 31930058) Health literacy ( 31250787) Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: CXADR MAL	7 interacting genes: A2M ACAN FURIN KRT40 KRTAP10-8 VCAN VEGFA
Entrez ID		120425	9510
HPRD ID		16482	05530
Ensembl ID		ENSG00000160593	ENSG00000154734
Uniprot IDs		B3KUI3 Q496M4 Q86YT9	B2RB33 Q9UHI8
PDB IDs			2JIH 2V4B 3Q2G 3Q2H
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?