PARD3B and INSC

Data Source:
HPRD (in vivo)

		PARD3B	INSC
Description		par-3 family cell polarity regulator beta	INSC spindle orientation adaptor protein
Image		No pdb structure
GO Annotations	Cellular Component	Adherens Junction Bicellular Tight Junction Cell Cortex Endomembrane System Apical Plasma Membrane Cell Junction Protein-containing Complex Apical Junction Complex	Plasma Membrane Cell Cortex Protein-containing Complex Apical Cortex
	Molecular Function	Protein Binding Phosphatidylinositol Binding	Protein Binding Cytoskeletal Anchor Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity
	Biological Process	Microtubule Cytoskeleton Organization Cell Cycle Cell Adhesion Protein Localization Establishment Of Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell Division Establishment Of Centrosome Localization	Establishment Of Mitotic Spindle Orientation Nervous System Development Asymmetric Cell Division Regulation Of Asymmetric Cell Division Cell Differentiation Regulation Of Protein Stability Apical Protein Localization
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) AIDS progression ( 21502085) Aluminium levels ( 26025379) Attention deficit hyperactivity disorder ( 30563984) Autism ( 22843504) Body mass index ( 28892062) Craniofacial microsomia ( 26853712) Diisocyanate-induced asthma ( 25918132) General risk tolerance (MTAG) ( 30643258) Hip circumference adjusted for BMI ( 28552196) Hippocampal volume ( 25625606) Idiopathic dilated cardiomyopathy ( 29495422) Intracranial aneurysm ( 29531279) Intraocular pressure ( 29617998 29785010 31959993 30054594) Knee osteoarthritis ( 18471798) Nicotine dependence symptom count ( 25555482) Post bronchodilator FEV1/FVC ratio ( 26634245) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Expressive vocabulary in infants ( 25226531) Heel bone mineral density ( 30598549 28869591) Menarche (age at onset) ( 23667675) Obesity-related traits ( 23251661)
Interacting Genes		9 interacting genes: CASK GAA INSC MARK2 PARD6B RBM5 RPS6KA1 YWHAE YWHAG	17 interacting genes: CCDC187 GEM GPANK1 GPSM1 GPSM2 LHX3 LNX1 PARD3 PARD3B PRR35 RUSC1 SMARCD1 SORBS3 TEKT3 TTC23 USP54 ZNF587
Entrez ID		117583	387755
HPRD ID		09795	18803
Ensembl ID		ENSG00000116117	ENSG00000188487
Uniprot IDs		Q8TEW8	Q1MX18
PDB IDs			3SF4
Enriched GO Terms of Interacting Partners?
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