AP1S1 and TNFRSF9

Data Source:
BioGRID (genetic interference)

		AP1S1	TNFRSF9
Description		adaptor related protein complex 1 subunit sigma 1	TNF receptor superfamily member 9
Image
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin-coated Pit Membrane AP-1 Adaptor Complex Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function		Protein Binding Cytokine Binding Signaling Receptor Activity
	Biological Process	Intracellular Protein Transport Receptor-mediated Endocytosis Response To Virus Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus	Apoptotic Process Negative Regulation Of Cell Population Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Cell Population Proliferation
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	TNFs bind their physiological receptors
Drugs			Urelumab
Diseases
GWAS		Adult body size ( 32376654)	Blond vs. brown/black hair color ( 30531825) Celiac disease ( 20190752) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Psoriasis ( 25903422 23143594) Rheumatoid arthritis ( 30423114 24390342) Ulcerative colitis ( 28067908 21297633) Waist-hip ratio ( 28552196)
Interacting Genes		6 interacting genes: AP1G1 AP1G2 AP1M2 AP2A2 PICK1 RHOU	7 interacting genes: LRR1 SERP1 TNFRSF4 TNFSF9 TRAF1 TRAF2 TRAF3
Entrez ID		1174	3604
HPRD ID		04635	03767
Ensembl ID		ENSG00000106367	ENSG00000049249
Uniprot IDs		A0A024QYT6 P61966	Q07011
PDB IDs		4P6Z	6A3V 6A3W 6BWV 6CPR 6CU0 6MGP 6MHR 6MI2
Enriched GO Terms of Interacting Partners?
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