RAB3IP and TXNDC5

Data Source:
BioGRID (two hybrid)

		RAB3IP	TXNDC5
Description		RAB3A interacting protein	thioredoxin domain containing 5
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GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Lamellipodium Golgi To Plasma Membrane Transport Vesicle	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Disulfide Isomerase Activity Protein Binding
	Biological Process	Protein Targeting To Membrane Exocytosis Regulation Of Catalytic Activity Ciliary Basal Body-plasma Membrane Docking	Protein Phosphopantetheinylation Negative Regulation Of Apoptotic Process Apoptotic Cell Clearance Neutrophil Degranulation
Pathways		Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs	Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)	Blood protein levels ( 30072576 29875488) High chromosomal aberration frequency (chromatid type) ( 31586183) Mean corpuscular hemoglobin ( 32888494) Pelvic organ prolapse ( 32184442)
Interacting Genes		32 interacting genes: BANP CCDC196 CHCHD3 DNAJB13 FAM124A KRT40 MB21D2 MBD3 MVP NAA10 PEG10 PKN1 PLOD3 PPL PRKAB2 RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TBC1D21 TEPSIN TRAPPC6A TXNDC5 ZBTB16 ZNF410 ZNF76	27 interacting genes: APP AR BLZF1 EDEM3 EFEMP1 FLACC1 GMPPB KRT38 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 LHX4 MGAT5B NOTCH2NLA PJA1 PRDX2 RAB3IP SPRY2 TRIM23 TRIM42 TRIP6 UBQLN2
Entrez ID		117177	81567
HPRD ID		10565	18249
Ensembl ID		ENSG00000127328	ENSG00000239264
Uniprot IDs		Q96QF0	A0A024QZV0 Q8NBS9
PDB IDs		4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P	2DIZ 3UJ1 3UVT 3WGD 3WGE 3WGX
Enriched GO Terms of Interacting Partners?
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