MRPL53 and KIF2A

Data Source:
BioGRID (two hybrid, two hybrid)

		MRPL53	KIF2A
Description		mitochondrial ribosomal protein L53	kinesin family member 2A
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit	Spindle Pole Nucleoplasm Nucleolus Cytoplasm Centrosome Centriole Spindle Cytosol Kinesin Complex Microtubule Spindle Microtubule Membrane Nuclear Body Centriolar Subdistal Appendage
	Molecular Function	Protein Binding	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Mitochondrial Translational Elongation Mitochondrial Translational Termination	Microtubule Cytoskeleton Organization Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Microtubule Depolymerization Mitotic Spindle Organization Nervous System Development Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cell Differentiation Regulation Of Cell Migration Cell Division Mitotic Spindle Assembly
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins
Drugs
Diseases
GWAS			Diastolic blood pressure ( 30224653) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		14 interacting genes: ANKRD29 APP ELOB GATD3B GSC2 HNRNPH1 IKZF3 KIF2A NFKBID PAX6 SMARCB1 SSX2IP TAX1BP1 THAP1	13 interacting genes: CASK CLSTN1 DYNLT1 FAM13C FXR2 H3-4 KLC1 KLC2 LARP1B LMO2 LMO3 MRPL53 SUMO2
Entrez ID		116540	3796
HPRD ID		14771	03996
Ensembl ID		ENSG00000204822	ENSG00000068796
Uniprot IDs		Q96EL3	A0A6Q8PFA6 B0AZS5 O00139
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG	2GRY 6BBN
Enriched GO Terms of Interacting Partners?
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