TRMT61A and ADSS1

Data Source:
HPRD (two hybrid)

		TRMT61A	ADSS1
Description		tRNA methyltransferase 61A	adenylosuccinate synthase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm TRNA (m1A) Methyltransferase Complex	Cytoplasm Cytosol
	Molecular Function	Protein Binding TRNA (adenine-N1-)-methyltransferase Activity MRNA (adenine-N1-)-methyltransferase Activity	Magnesium Ion Binding GTPase Activity Adenylosuccinate Synthase Activity GTP Binding Phosphate Ion Binding Identical Protein Binding Actin Filament Binding
	Biological Process	TRNA Modification TRNA Methylation MRNA Methylation	Immune System Process AMP Biosynthetic Process Aspartate Metabolic Process Glutamine Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Response To Muscle Activity Cellular Response To Drug Response To Starvation 'de Novo' AMP Biosynthetic Process IMP Metabolic Process Cellular Response To Electrical Stimulus
Pathways		tRNA modification in the nucleus and cytosol	Purine ribonucleoside monophosphate biosynthesis
Drugs			Aspartic acid Hadacidin 6-O-Phosphoryl Inosine Monophosphate Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate Adenylosuccinic acid Inosinic Acid Alanosine
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Branched-chain amino acid levels (Isoleucine) ( 27898682) Extremely high intelligence ( 29520040) Hemoglobin levels ( 32327693) Intelligence (MTAG) ( 29326435) Mean corpuscular volume ( 32888494 27863252) Red blood cell count ( 32888494) Schizophrenia ( 25056061)
Interacting Genes		2 interacting genes: TCL1A TRMT6	2 interacting genes: AZIN1 LYAR
Entrez ID		115708	122622
HPRD ID		08810	12433
Ensembl ID		ENSG00000166166	ENSG00000185100
Uniprot IDs		A0A024R6Q2 Q96FX7	B3KTV4 Q8N142
PDB IDs		5CCB 5CCX 5CD1	2GJO
Enriched GO Terms of Interacting Partners?
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