EVI5L and RAB10

Data Source:
BioGRID (two hybrid)

		EVI5L	RAB10
Description		ecotropic viral integration site 5 like	RAB10, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Exocyst Endosome Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Cilium Synaptic Vesicle Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Exocytic Vesicle Endoplasmic Reticulum Tubular Network
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Intracellular Protein Transport Positive Regulation Of GTPase Activity Activation Of GTPase Activity Negative Regulation Of Cilium Assembly	Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Axonogenesis Protein Secretion Vesicle-mediated Transport Endosomal Transport Regulation Of Exocytosis Antigen Processing And Presentation Polarized Epithelial Cell Differentiation Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Neutrophil Degranulation Regulated Exocytosis Establishment Of Neuroblast Polarity Endoplasmic Reticulum Tubular Network Organization Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell-cell Adhesion Protein Localization To Basolateral Plasma Membrane
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		HIV-1 viral setpoint ( 20205591) Menarche (age at onset) ( 25231870)	Apolipoprotein B levels ( 32203549) Immune response to smallpox vaccine (IL-6) ( 22542470) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Metabolite levels (HVA/MHPG ratio) ( 23319000) Platelet distribution width ( 32888494)
Interacting Genes		15 interacting genes: A2M ANKRD36 AP1M1 CCDC185 GAS8 KRT79 LNX1 NUDT18 PRPF18 PSEN2 RAB10 RBM7 SRPK2 TBC1D21 ZNF648	9 interacting genes: APP ENOPH1 EVI5L MICAL1 MTNR1A PPBP RABIF RIMS1 SEPTIN9
Entrez ID		115704	10890
HPRD ID		10044	06692
Ensembl ID		ENSG00000142459	ENSG00000084733
Uniprot IDs		A0A384MR55 Q96CN4	P61026
PDB IDs			5LPN 5SZJ
Enriched GO Terms of Interacting Partners?
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