CKB and FUT8

Data Source:
BioGRID (biochemical)

		CKB	FUT8
Description		creatine kinase B	fucosyltransferase 8
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Dendrite Neuronal Cell Body Extracellular Exosome	Golgi Membrane Golgi Apparatus Membrane Integral Component Of Membrane Golgi Cisterna Membrane Extracellular Exosome
	Molecular Function	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Ubiquitin Protein Ligase Binding	Protein Binding Glycoprotein 6-alpha-L-fucosyltransferase Activity SH3 Domain Binding Alpha-(1->6)-fucosyltransferase Activity
	Biological Process	Creatine Metabolic Process Phosphorylation Cerebellum Development Substantia Nigra Development Cellular Chloride Ion Homeostasis Phosphocreatine Biosynthetic Process	In Utero Embryonic Development Protein N-linked Glycosylation N-glycan Processing Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Respiratory Gaseous Exchange By Respiratory System Oligosaccharide Biosynthetic Process Regulation Of Gene Expression Cell Migration Protein N-linked Glycosylation Via Asparagine Protein Glycosylation In Golgi N-glycan Fucosylation L-fucose Catabolic Process Receptor Metabolic Process GDP-L-fucose Metabolic Process Regulation Of Cellular Response To Oxidative Stress
Pathways		Creatine metabolism	Maturation of spike protein Reactions specific to the complex N-glycan synthesis pathway
Drugs		Creatine Phosphocreatine
Diseases
GWAS		Adult body size ( 32376654) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Extremely high intelligence ( 29520040) Height ( 28552196 31562340) Schizophrenia ( 25056061)	Blood protein levels ( 29875488) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Hematocrit ( 32888494) Hemoglobin ( 32888494) High density lipoprotein cholesterol levels ( 29083408) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG monosialylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392 32128391) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Ischemic stroke ( 26732560) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Menarche (age at onset) ( 25231870) Multiple sclerosis--Brain Glutamate Levels ( 20802204) N-glycan levels ( 21908519 21203500 31163085) Obesity-related traits ( 23251661) Post bronchodilator FEV1/FVC ratio ( 26634245) Red blood cell count ( 32888494) Systemising ( 31508503) Verbal-numerical reasoning ( 27046643)
Interacting Genes		15 interacting genes: ACD ARIH2 ASB9 CKM ERBB2 GOLGA2 ILK MLH1 POT1 PPP1CA SERP2 TAB1 TERF1 TINF2 TRIM63	2 interacting genes: FBXO7 ZBTB10
Entrez ID		1152	2530
HPRD ID		00423	03994
Ensembl ID		ENSG00000166165	ENSG00000033170
Uniprot IDs		G3V4N7 P12277 V9HWH2	A8K8P8 Q546E0 Q9BYC5
PDB IDs		3B6R 3DRB 3DRE 6V9H	2DE0 6VLD 6VLE 6X5H 6X5R 6X5S 6X5T 6X5U
Enriched GO Terms of Interacting Partners?
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