VASN and LCE2D

Data Source:
BioGRID (two hybrid)

		VASN	LCE2D
Description		vasorin	late cornified envelope 2D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Lysosomal Membrane Plasma Membrane Cell Surface Integral Component Of Membrane Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding Cadherin Binding Transforming Growth Factor Beta Binding	Protein Binding
	Biological Process	Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Hypoxia Cellular Response To Redox State	Keratinization
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS		Erectile dysfunction ( 30583798) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		53 interacting genes: ADAMTSL4 AQP3 CIB4 CYSRT1 GRN GUCD1 HOXA1 KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP4-2 KRTAP5-11 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1C LCE2A LCE2C LCE2D LCE4A LNX1 MDFI MEOX2 MTUS2 NBPF19 NOTCH2NLA NR4A3 RGS17 RGS19 RGS20 RNF31 SMCP SSC4D TGFB1 TGFB2 TGFB3 TGM1 TRIP6 VWC2	55 interacting genes: ADAMTSL4 CYSRT1 EFEMP2 GLRX3 GRN GUCD1 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-5 KRTAP10-6 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP17-1 KRTAP19-2 KRTAP2-3 KRTAP2-4 KRTAP4-1 KRTAP4-12 KRTAP4-2 KRTAP5-2 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2B LCE2C NBPF19 NCALD NOTCH2NLA NR4A3 NUFIP2 OTX1 P4HB PLA2G10 PLSCR1 RGS20 RNF4 SLC39A7 SMCP SPRY1 SPRY2 SUMO1P1 TRIM42 TSPAN4 VASN VWC2
Entrez ID		114990	353141
HPRD ID		10587	17261
Ensembl ID		ENSG00000168140	ENSG00000187223
Uniprot IDs		Q6EMK4	Q5TA82
PDB IDs
Enriched GO Terms of Interacting Partners?
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