GALNT13 and SCN2A

Data Source:
HPRD (in vivo)

		GALNT13	SCN2A
Description		polypeptide N-acetylgalactosaminyltransferase 13	sodium voltage-gated channel alpha subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Voltage-gated Sodium Channel Complex Plasma Membrane Integral Component Of Plasma Membrane Intercalated Disc Membrane T-tubule Axon Intrinsic Component Of Plasma Membrane Node Of Ranvier Paranode Region Of Axon Sodium Channel Complex Glutamatergic Synapse Integral Component Of Presynaptic Membrane
	Molecular Function	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding	Voltage-gated Ion Channel Activity Voltage-gated Sodium Channel Activity
	Biological Process	O-glycan Processing Protein Phosphopantetheinylation Protein O-linked Glycosylation Via Serine Protein O-linked Glycosylation Via Threonine	Sodium Ion Transport Nervous System Development Memory Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Myelination Neuron Apoptotic Process Cellular Response To Hypoxia Membrane Depolarization During Action Potential
Pathways		O-linked glycosylation of mucins	Interaction between L1 and Ankyrins Phase 0 - rapid depolarisation
Drugs			Tramadol Ranolazine Phenytoin Topiramate Valproic acid Lamotrigine Carbamazepine Oxcarbazepine Propofol Cocaine Zonisamide Promethazine Tetrodotoxin Brivaracetam Tetracaine Amylocaine Propoxycaine Pramocaine Pentoxyverine Dichlorobenzyl alcohol Metergoline Bioallethrin Amylmetacresol Fish oil
Diseases			Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS		Aging traits ( 17903295) Blood trace element (Zn levels) ( 23720494) Body mass index ( 24348519) Coronary artery disease in type 1 diabetes ( 29695241) Forced expiratory volume in 1 second (occupational environmental exposures interaction) ( 25979521) Liver enzyme levels (alanine transaminase) ( 24124411) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Obesity-related traits ( 23251661) Placental abruption ( 29884306) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Schizophrenia or schizoaffective disorder ( 31591465) Triiodothyronine levels and thyroxine levels ( 30843173)	Adult body size ( 32376654) Bipolar disorder ( 31043756) Diastolic blood pressure ( 30224653) Epilepsy ( 30531953) Factor VII activity ( 30642921) Febrile seizures ( 25344690) Febrile seizures (MMR vaccine-related) ( 25344690) Febrile seizures (MMR vaccine-unrelated) ( 25344690) Focal epilepsy ( 30531953) Generalized epilepsy ( 30531953) Periodontitis (DPAL) ( 24024966) Refractive error ( 32231278) Trunk fat mass ( 28552196) Urinary sodium excretion ( 31409800)
Interacting Genes		2 interacting genes: EXOSC2 SKIV2L	5 interacting genes: ANK3 ARHGEF10L MPP3 RNF130 SCN4B
Entrez ID		114805	6326
HPRD ID		16325	03133
Ensembl ID		ENSG00000144278	ENSG00000136531
Uniprot IDs		B3KY85 Q8IUC8	Q99250
PDB IDs			2KAV 4JPZ 4RLY 6BUT 6J8E
Enriched GO Terms of Interacting Partners?
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