CCDC85A and PFDN1

Data Source:
BioGRID (two hybrid)

		CCDC85A	PFDN1
Description		coiled-coil domain containing 85A	prefoldin subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Adherens Junction	Cytoplasm Prefoldin Complex
	Molecular Function	Protein Binding	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Biological_process	Protein Folding Negative Regulation Of Amyloid Fibril Formation
Pathways			Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Copper levels ( 26025379) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Menarche (age at onset) ( 21102462 25231870) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Type 2 diabetes ( 26818947)	Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)
Interacting Genes		5 interacting genes: NEK2 PFDN1 STMN2 SYTL5 TP53BP2	54 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235
Entrez ID		114800	5201
HPRD ID		19098	05357
Ensembl ID		ENSG00000055813	ENSG00000113068
Uniprot IDs		Q96PX6	O60925
PDB IDs			6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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