VSIG4 and VAMP5

Data Source:
BioGRID (two hybrid)

		VSIG4	VAMP5
Description		V-set and immunoglobulin domain containing 4	vesicle associated membrane protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Protein-containing Complex	Late Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Intercalated Disc Cytoplasmic Vesicle Membrane Integral Component Of Organelle Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Complement Component C3b Binding Protein Binding	Protein Binding
	Biological Process	Complement Activation, Alternative Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of T Cell Proliferation Negative Regulation Of Macrophage Activation Negative Regulation Of Complement Activation, Alternative Pathway	Muscle Organ Development Skeletal Muscle Tissue Development Cell Differentiation Golgi To Plasma Membrane Protein Transport
Pathways
Drugs
Diseases
GWAS		Male-pattern baldness ( 28196072) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Coronary artery disease ( 29212778 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Myocardial infarction ( 26343387) Platelet distribution width ( 32888494) Prostate cancer ( 21743467) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		7 interacting genes: APP C3 FATE1 JAGN1 PDK2 TRIM72 VAMP5	59 interacting genes: ABHD16A AQP6 ASGR2 ATP6AP2 BIK CD53 CLDN5 CLDN7 COMT CPLX4 CYB5R3 ELOVL4 FAM209A FNDC9 GJA8 GORAB GPR152 GPX8 GRAMD2B HIBADH IL3RA JAGN1 KIR2DL3 KIR3DL3 KLRC1 LMNA LRRC25 MDC1 MUC1 NCAPH2 PANX1 PLAC8 PVR RETREG3 SAR1A SLC14A2 SLC18A1 SNAP29 SPINT1 STX16 STX1A STX1B STX2 STX4 STX5 STX8 TAS2R5 TM4SF18 TMCO5A TMEM106C TMEM139 TMEM14B TMEM31 TMEM45B TMEM52B TMEM86B TMPRSS2 TMX2 VSIG4
Entrez ID		11326	10791
HPRD ID		02286	09513
Ensembl ID		ENSG00000155659	ENSG00000168899
Uniprot IDs		Q9Y279	O95183 Q6FG93
PDB IDs		2ICC 2ICE 2ICF 5IMK 5IML
Enriched GO Terms of Interacting Partners?
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