RDH13 and CYP3A5

Data Source:
BioGRID (two hybrid)

		RDH13	CYP3A5
Description		retinol dehydrogenase 13	cytochrome P450 family 3 subfamily A member 5
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane	Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	NADP-retinol Dehydrogenase Activity	Monooxygenase Activity Iron Ion Binding Protein Binding Steroid Hydroxylase Activity Retinoic Acid 4-hydroxylase Activity Oxidoreductase Activity Oxygen Binding Heme Binding Testosterone 6-beta-hydroxylase Activity Aromatase Activity Estrogen 16-alpha-hydroxylase Activity
	Biological Process	Response To High Light Intensity Retina Layer Formation Eye Photoreceptor Cell Development Retinol Metabolic Process Retinal Metabolic Process	Lipid Hydroxylation Xenobiotic Metabolic Process Steroid Metabolic Process Estrogen Metabolic Process Alkaloid Catabolic Process Retinol Metabolic Process Retinoic Acid Metabolic Process Drug Catabolic Process Oxidative Demethylation
Pathways		RA biosynthesis pathway	Xenobiotics Aflatoxin activation and detoxification
Drugs		Vitamin A	Cannabidiol Diacerein Nabiximols
Diseases
GWAS		Blood protein levels ( 28240269) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494)	Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Platelet count ( 29403010) Serum metabolite levels ( 23093944) Ticagrelor levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		3 interacting genes: CYP3A5 GADD45G PSKH1	3 interacting genes: ATOH8 ETV5 RDH13
Entrez ID		112724	1577
HPRD ID		17963	05617
Ensembl ID		ENSG00000160439	ENSG00000106258
Uniprot IDs		A0A024R4M8 B3KVA3 Q8NBN7	B7Z3P6 P20815
PDB IDs			5VEU
Enriched GO Terms of Interacting Partners?
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