ZHX1 and TALDO1

Data Source:
HPRD (two hybrid)

		ZHX1	TALDO1
Description		zinc fingers and homeoboxes 1	transaldolase 1
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Intracellular Anatomical Structure Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Protein Heterodimerization Activity	Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate Glyceronetransferase Activity Protein Binding Monosaccharide Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Carbohydrate Metabolic Process Xylulose Biosynthetic Process Fructose 6-phosphate Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Non-oxidative Branch Glyceraldehyde-3-phosphate Metabolic Process Interleukin-12-mediated Signaling Pathway
Pathways			Insulin effects increased synthesis of Xylulose-5-Phosphate TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P Pentose phosphate pathway Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS			Proteinuria and chronic kidney disease ( 26420894)
Interacting Genes		53 interacting genes: AKR1C3 AKT1 ATXN1 BARD1 BCL2L1 BHLHE40 BID CHD3 CREB1 CREBBP CSNK2A1 DDX39B DLST DYNLL1 EFNA2 ELL GADD45A GNG11 GSK3B HSPE1 IDH1 LAMA4 LYAR MPHOSPH6 NACA NFYA PAFAH1B3 PEX14 PIAS4 PIGC PNP PRPF40A PSMD11 SAT1 SERPINB9 SUMO1 SUMO2 TAL1 TALDO1 TARDBP TERF1 TNFRSF10C TOLLIP TP53 UBC UTP3 VIM WDR33 ZHX2 ZHX3 ZMYND11 ZNF33B ZYX	7 interacting genes: LSM8 PEA15 TERF1 TERF2 TERF2IP UBE3A ZHX1
Entrez ID		11244	6888
HPRD ID		10379	03640
Ensembl ID		ENSG00000165156	ENSG00000177156
Uniprot IDs		A0A024R9F1 Q9UKY1	A0A140VK56 P37837
PDB IDs		2ECB 2GHF 2LY9 3NAR	1F05
Enriched GO Terms of Interacting Partners?
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