HPS5 and ITGA3

Data Source:
HPRD (two hybrid)

		HPS5	ITGA3
Description		HPS5 biogenesis of lysosomal organelles complex 2 subunit 2	integrin subunit alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol BLOC-2 Complex	Plasma Membrane Focal Adhesion Integrin Complex External Side Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Filopodium Membrane Integrin Alpha3-beta1 Complex Receptor Complex Perinuclear Region Of Cytoplasm Excitatory Synapse Extracellular Exosome Cell Periphery Synaptic Membrane Growth Cone Filopodium
	Molecular Function	Protein Binding	Fibronectin Binding Protease Binding Integrin Binding Protein Binding Collagen Binding Protein Domain Specific Binding Laminin Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Organelle Organization Blood Coagulation Pigmentation	Neuron Migration Cell-matrix Adhesion Integrin-mediated Signaling Pathway Heart Development Memory Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Neuron Projection Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Wnt Signaling Pathway Extracellular Matrix Organization Lung Development Regulation Of BMP Signaling Pathway Negative Regulation Of Cell Projection Organization Response To Gonadotropin Negative Regulation Of Rho Protein Signal Transduction Exploration Behavior Response To Drug Skin Development Mesodermal Cell Differentiation Leukocyte Migration Maternal Process Involved In Female Pregnancy Nephron Development Dendritic Spine Maintenance Renal Filtration Positive Regulation Of Protein Localization To Plasma Membrane
Pathways			Basigin interactions Integrin cell surface interactions Integrin cell surface interactions Laminin interactions MET activates PTK2 signaling
Drugs
Diseases		Hermansky-Pudlak syndrome (HPS)
GWAS		Amyloid A serum levels ( 21124955) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Metabolic traits ( 21886157) Serum metabolite levels ( 23093944) Survival in pancreatic cancer ( 28470677) Triglyceride levels ( 32203549)
Interacting Genes		2 interacting genes: HPS6 ITGA3	15 interacting genes: ADAM9 BIN1 CALR CD151 CD82 CD9 FHL2 FN1 HPS5 HSPD1 ITGB1 LGALS8 RABIF TIMP2 TSPAN4
Entrez ID		11234	3675
HPRD ID		07395	05431
Ensembl ID		ENSG00000110756	ENSG00000005884
Uniprot IDs		Q9UPZ3	A0A140VJM0 P26006
PDB IDs
Enriched GO Terms of Interacting Partners?
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