POLR3A and POLR3E

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		POLR3A	POLR3E
Description		RNA polymerase III subunit A	RNA polymerase III subunit E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase III Complex Cytosol Membrane	Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	DNA Binding Chromatin Binding DNA-directed 5'-3' RNA Polymerase Activity Metal Ion Binding	DNA-directed 5'-3' RNA Polymerase Activity
	Biological Process	Transcription, DNA-templated Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Defense Response To Virus	Transcription, DNA-templated Positive Regulation Of Type I Interferon Production Innate Immune Response Defense Response To Virus
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Colorectal cancer or advanced adenoma ( 30510241) Executive function (trail making test B) ( 24629169)	Height ( 31562340) L-selectin levels ( 25576479)
Interacting Genes		6 interacting genes: EWSR1 IKBKG NEDD4 PCBD1 PKP2 POLR3E	2 interacting genes: POLR3A POLR3D
Entrez ID		11128	55718
HPRD ID		17879	15155
Ensembl ID		ENSG00000148606	ENSG00000058600
Uniprot IDs		O14802	A0A0C4DH01 Q9NVU0
PDB IDs
Enriched GO Terms of Interacting Partners?
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