CIT and DERA

Data Source:
BioGRID (affinity chromatography technology)

		CIT	DERA
Description		citron rho-interacting serine/threonine kinase	deoxyribose-phosphate aldolase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Membrane	Extracellular Region Nucleoplasm Cytosol Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Transcription Coactivator Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding SH3 Domain Binding Protein Kinase Binding PDZ Domain Binding Protein Serine/threonine Kinase Inhibitor Activity Metal Ion Binding Scaffold Protein Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Deoxyribose-phosphate Aldolase Activity Protein Binding
	Biological Process	Mitotic Cell Cycle Mitotic Cytokinesis Peptidyl-threonine Phosphorylation Actomyosin Structure Organization Positive Regulation Of Cytokinesis Negative Regulation Of Hippo Signaling Intracellular Signal Transduction Generation Of Neurons Neuron Apoptotic Process Negative Regulation Of Protein Serine/threonine Kinase Activity	Pentose-phosphate Shunt Deoxyribonucleotide Catabolic Process Carbohydrate Catabolic Process Neutrophil Degranulation Deoxyribonucleoside Catabolic Process Deoxyribose Phosphate Catabolic Process
Pathways		RHO GTPases activate CIT RHO GTPases activate CIT	Neutrophil degranulation Pentose phosphate pathway
Drugs		Fostamatinib
Diseases
GWAS		Number of sexual partners ( 30643258) Urgency urinary incontinence ( 25524241)	Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054) Bone mineral density (hip) and age at menarche ( 26312577) Chronotype ( 30696823) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)
Interacting Genes		10 interacting genes: DISC1 DLG4 GRIN1 GRIN2D MTNR1A RAC1 RHOA RHOB RHOC RND3	2 interacting genes: ALDH16A1 HSF2
Entrez ID		11113	51071
HPRD ID		09289	13138
Ensembl ID		ENSG00000122966	ENSG00000023697
Uniprot IDs		O14578	E9PPM8 Q9Y315
PDB IDs
Enriched GO Terms of Interacting Partners?
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