PIM2 and RPL21

Data Source:
HPRD (two hybrid)

		PIM2	RPL21
Description		Pim-2 proto-oncogene, serine/threonine kinase	ribosomal protein L21
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GO Annotations	Cellular Component	Cytoplasm	Endoplasmic Reticulum Cytosol Membrane Cytosolic Large Ribosomal Subunit
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Population Proliferation Response To Virus Positive Regulation Of Autophagy Negative Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Protein Stabilization	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Electrocardiographic traits ( 17903306) Estimated glomerular filtration rate ( 31451708)
Interacting Genes		15 interacting genes: ATXN1 BAD CUTC DAPK1 FBH1 FBXO7 GSK3B HNRNPH3 HSF1 IKBKG NDUFB8 RPL21 SOCS1 TRIM14 ZNF821	5 interacting genes: DUX4 HNRNPA1 PIM2 PTEN VHL
Entrez ID		11040	6144
HPRD ID		02244	04700
Ensembl ID		ENSG00000102096	ENSG00000122026
Uniprot IDs		A0A024QYW7 Q9P1W9	P46778 Q6IAX2
PDB IDs		2IWI 4X7Q	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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