KIF2C and ZNF566

Data Source:
BioGRID (two hybrid)

		KIF2C	ZNF566
Description		kinesin family member 2C	zinc finger protein 566
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Nucleus Centrosome Spindle Cytosol Kinesin Complex Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Membrane Microtubule Plus-end	Nucleus
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Centromeric DNA Binding Microtubule Plus-end Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Microtubule Depolymerization Mitotic Metaphase Plate Congression Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Cell Division Metaphase Plate Congression Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Chromosome Segregation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins	Generic Transcription Pathway
Drugs		Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS
Interacting Genes		10 interacting genes: APP AURKA CENPH CSNK2B H3-4 NDEL1 PLK1 SUMO2 VHL ZNF566	6 interacting genes: EXOC8 KIF2C KIF9 MAGOHB TRIM55 TRIM63
Entrez ID		11004	84924
HPRD ID		05172	15847
Ensembl ID		ENSG00000142945	ENSG00000186017
Uniprot IDs		A0A140VKF1 B7Z6Q6 B7Z7M6 Q99661	B4DRR6 Q969W8
PDB IDs		2HEH 4UBF 4Y05 5MIO
Enriched GO Terms of Interacting Partners?
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