KIF2C and PMPCA

Data Source:
BioGRID (affinity chromatography technology)

		KIF2C	PMPCA
Description		kinesin family member 2C	peptidase, mitochondrial processing subunit alpha
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Nucleus Centrosome Spindle Cytosol Kinesin Complex Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Membrane Microtubule Plus-end	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Centromeric DNA Binding Microtubule Plus-end Binding	Protein Binding Metal Ion Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Microtubule Depolymerization Mitotic Metaphase Plate Congression Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Cell Division Metaphase Plate Congression Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Chromosome Segregation	Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins	Mitochondrial protein import Processing of SMDT1
Drugs		Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS			Apolipoprotein B levels ( 32203549) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Joint damage in rheumatoid arthritis ( 26498133) LDL cholesterol levels ( 32203549) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)
Interacting Genes		10 interacting genes: APP AURKA CENPH CSNK2B H3-4 NDEL1 PLK1 SUMO2 VHL ZNF566	5 interacting genes: BMPR2 LINC01554 PMPCB SKIV2L ZNF76
Entrez ID		11004	23203
HPRD ID		05172	07500
Ensembl ID		ENSG00000142945	ENSG00000165688
Uniprot IDs		A0A140VKF1 B7Z6Q6 B7Z7M6 Q99661	Q10713
PDB IDs		2HEH 4UBF 4Y05 5MIO
Enriched GO Terms of Interacting Partners?
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