SLC27A2 and PDE6G

Data Source:
BioGRID (pull down)

		SLC27A2	PDE6G
Description		solute carrier family 27 member 2	phosphodiesterase 6G
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Specific Granule Membrane Extracellular Exosome	Plasma Membrane Photoreceptor Outer Segment Membrane Photoreceptor Disc Membrane
	Molecular Function	Long-chain Fatty Acid-CoA Ligase Activity Long-chain Fatty Acid Transporter Activity ATP Binding Fatty Acid Transmembrane Transporter Activity Enzyme Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity Cholate-CoA Ligase Activity Phytanate-CoA Ligase Activity Pristanate-CoA Ligase Activity	Enzyme Inhibitor Activity Protein Binding Spectrin Binding CGMP Binding 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Fatty Acid Alpha-oxidation Long-chain Fatty Acid Metabolic Process Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Very Long-chain Fatty Acid Catabolic Process Neutrophil Degranulation Long-chain Fatty Acid Import Into Cell Methyl-branched Fatty Acid Metabolic Process	Activation Of MAPK Activity Wnt Signaling Pathway, Calcium Modulating Pathway Visual Perception Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Negative Regulation Of Catalytic Activity Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of G Protein-coupled Receptor Signaling Pathway
Pathways		Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol Alpha-oxidation of phytanate Neutrophil degranulation Peroxisomal protein import Peroxisomal protein import	Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Ca2+ pathway Ca2+ pathway
Drugs			Sildenafil Vardenafil 3-isobutyl-1-methyl-7H-xanthine
Diseases			Retinitis pigmentosa (RP)
GWAS		Blood metabolite ratios ( 24816252) Platelet count ( 32888494) Verbal declarative memory ( 25648963)	Blond vs. brown/black hair color ( 30531825) High myopia ( 31816047) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: ABCD1 PEX5 UBC YWHAQ	11 interacting genes: BHLHE40 DNM2 FNBP1 GNAO1 GRB2 GRK2 L3MBTL3 MAPK3 PRKAB2 SRC TRIP10
Entrez ID		11001	5148
HPRD ID		11935	08914
Ensembl ID		ENSG00000140284	ENSG00000185527
Uniprot IDs		O14975	P18545
PDB IDs			3JWR
Enriched GO Terms of Interacting Partners?
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